Tag Archive : gelston house east haddam ct

corbettresearch
10 Sep

G-quadruplex DNA and RNA:

By Nicolas Antibodies , Enzymes , Exosomes , Gels , PCR , Western Blot , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , No Comments

G-quadruplex DNA and RNA: Their roles in regulation of DNA replication and other biological functions

  • G-quadruplex is one of the best-studied non-B type DNA that is now known to be prevalently present in the genomes of almost all the biological species. Recent studies reveal roles of G-quadruplex (G4) structures in various nucleic acids and chromosome transactions.
  • In this short article, we will first describe recent findings on the roles of G4 in regulation of DNA replication. G4 is involved in regulation of spatio-temporal regulation of DNA replication through interaction with a specific binding protein, Rif1. This regulation is at least partially mediated by generation of specific chromatin architecture through Rif1-G4 interactions.
  • We will also describe recent studies showing the potential roles of G4 in initiation of DNA replication. Next, we will present showcases of highly diversified roles of DNA G4 and RNA G4 in regulation of nucleic acid and chromosome functions. Finally, we will discuss how the formation of cellular G4 could be regulated.
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DNA / RNA Damage Antibody
abx440321-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx440602-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx440883-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx441164-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx441445-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx441726-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442007-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442850-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx443130-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx443410-100ug 100 ug
EUR 644.4

DNA / RNA Damage Antibody
abx443691-100ug 100 ug
EUR 678

DNA / RNA Damage Antibody
abx443972-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442288-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442569-100ug 100 ug
EUR 661.2

Monoclonal antibody for DNA/RNA Damage
SMC-155C 0.025mg
EUR 228
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

Monoclonal antibody for DNA/RNA Damage
SMC-155D 0.1mg
EUR 398.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A390 0.1mg
EUR 454.8
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 390.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A488 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 488.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A565 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 565.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A594 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A633 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 633.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A655 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 655.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A680 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 680.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A700 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 700.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-ALP 0.1mg
EUR 446.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Alkaline Phosphatase.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-APC 0.1mg
EUR 452.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-APCCY7 0.1mg
EUR 540
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC/Cy7.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-BI 0.1mg
EUR 448.8
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Biotin.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY350 0.1mg
EUR 471.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 350.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY405 0.1mg
EUR 457.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 405.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY488 0.1mg
EUR 445.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 488.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY594 0.1mg
EUR 447.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY633 0.1mg
EUR 441.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 633.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-FITC 0.1mg
EUR 444
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with FITC.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-HRP 0.1mg
EUR 439.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with HRP.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-P594 0.1mg
EUR 462
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PE/ATTO 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-PCP 0.1mg
EUR 452.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PerCP.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-RPE 0.1mg
EUR 450
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with RPE.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-STR 0.1mg
EUR 451.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Streptavidin.

Monoclonal antibody for DNA/RNA Damage
SMC-155S 0.012mg
EUR 78
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (APC)
abx442602-100ug 100 ug
EUR 661.2

DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Human), APC
4-PAJ282Hu01-APC
  • EUR 414.00
  • EUR 3930.00
  • EUR 1094.40
  • EUR 528.00
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with APC.

DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Mouse), APC
4-PAJ282Mu01-APC
  • EUR 421.20
  • EUR 4038.00
  • EUR 1122.00
  • EUR 538.80
  • EUR 266.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with APC.

Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Mouse), APC
4-PAA319Mu01-APC
  • EUR 394.80
  • EUR 3649.20
  • EUR 1024.80
  • EUR 499.20
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with APC.

DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Human), APC-Cy7
4-PAJ282Hu01-APC-Cy7
  • EUR 685.20
  • EUR 7716.00
  • EUR 2046.00
  • EUR 912.00
  • EUR 382.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with APC-Cy7.

DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Mouse), APC-Cy7
4-PAJ282Mu01-APC-Cy7
  • EUR 699.60
  • EUR 7932.00
  • EUR 2100.00
  • EUR 933.60
  • EUR 388.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with APC-Cy7.

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx232284-100ug 100 ug
EUR 577.2

DNA Damage-Binding Protein 1 (DDB1) Antibody
20-abx333999
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody
20-abx338922
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Human, Mouse), APC
4-PAA319Hu01-APC
  • EUR 387.60
  • EUR 3541.20
  • EUR 997.20
  • EUR 488.40
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with APC.

Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Mouse), APC-Cy7
4-PAA319Mu01-APC-Cy7
  • EUR 645.60
  • EUR 7154.40
  • EUR 1905.60
  • EUR 855.60
  • EUR 364.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with APC-Cy7.

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx241498
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx103576
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx176186
  • EUR 1479.60
  • EUR 710.40
  • 1 mg
  • 200 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx172142
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx213754
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx332226-100ul 100 ul
EUR 510

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx326210
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx112119
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx112120
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx026524-400ul 400 ul
EUR 627.6

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx026524-80l 80 µl
EUR 343.2

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx027183-400ul 400 ul
EUR 627.6

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx027183-80l 80 µl
EUR 343.2

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx125748
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx125750
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx123209
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx129884
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx329652
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx000607
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx004988
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx301173
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
abx236289-100ug 100 ug
EUR 577.2

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
abx148746-100ug 100 ug
EUR 526.8

P53 And Dna Damage Regulated 1 (PDRG1) Antibody
20-abx114308
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx328877
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
abx340215-100ug 100 ug
EUR 469.2

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx008020
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx014692
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx301702
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 1 (DDB1) Antibody (HRP)
20-abx335376
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody (HRP)
20-abx335379
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

OxiSelect Nitrosative DNA/RNA Damage ELISA Kit (8-Nitroguanine Quantitation)
STA-825 96 assays
EUR 957.6
Description: The OxiSelect Nitrosative DNA/RNA Damage ELISA Kit is a competitive enzyme immunoassay developed for rapid detection and quantitation of 8-nitroguanine in urine, serum, or plasma samples.

OxiSelect Nitrosative DNA/RNA Damage ELISA Kit (8-Nitroguanine Quantitation)
STA-825-5 5 x 96 assays
EUR 3888
Description: The OxiSelect Nitrosative DNA/RNA Damage ELISA Kit is a competitive enzyme immunoassay developed for rapid detection and quantitation of 8-nitroguanine in urine, serum, or plasma samples.

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
20-abx316281
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
20-abx210264
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
abx235072-100ug 100 ug
EUR 661.2

Mediator of DNA Damage Checkpoint 1 (MDC1) Antibody
abx412564-01ml 0.1 ml
EUR 844.8

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
abx444922-100ug 100 ug
EUR 594

DNA Damage-Binding Protein 1 (DDB1) Antibody (FITC)
20-abx335377
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody (FITC)
20-abx335380
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
20-abx005807
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Induced Apoptosis Suppressor (DDIAS) Antibody
20-abx323435
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Human, Mouse), APC-Cy7
4-PAA319Hu01-APC-Cy7
  • EUR 631.20
  • EUR 6938.40
  • EUR 1851.60
  • EUR 834.00
  • EUR 358.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with APC-Cy7.

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx232285-100ug 100 ug
EUR 610.8

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
abx232286-100ug 100 ug
EUR 577.2

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
20-abx242438
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
20-abx242444
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
20-abx225140
  • EUR 444.00
  • EUR 727.20
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx219380-100ug 100 ug
EUR 526.8

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
20-abx141699
  • EUR 444.00
  • EUR 727.20
  • EUR 360.00
  • 100 ul
  • 200 ul
  • 50 ul

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx412503-01mg 0.1 mg
EUR 961.2

DNA Damage-Binding Protein 1 (DDB1) Antibody (Biotin)
20-abx335378
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody (Biotin)
20-abx335381
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
20-abx111958
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
20-abx111959
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
20-abx128508
  • EUR 477.60
  • EUR 159.60
  • EUR 1312.80
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
20-abx130944
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx432057-200ul 200 ul
EUR 460.8

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
20-abx001528
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
20-abx002127
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx159468-100ul 100 ul
EUR 560.4

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx159469-100ul 100 ul
EUR 560.4

P53 And DNA Damage Regulated 1 (PDRG1) Antibody (HRP)
20-abx311435
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (HRP)
20-abx303605
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (FITC)
20-abx303606
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

P53 And DNA Damage Regulated 1 (PDRG1) Antibody (FITC)
20-abx311436
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

EpiQuik Nitrosative (8-Nitroguanine) DNA/RNA Damage Quantification Kit (Colorimetric)
P-6009
  • EUR 486.20
  • EUR 775.50
  • 48 Assays
  • 96 Assays

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody
20-abx213755
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody
20-abx213756
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody
abx140150-01mg 0.1 mg
EUR 510

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody
20-abx112121
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody
20-abx302163
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a) Polyclonal Antibody (Rat), APC
4-PAL534Ra01-APC
  • EUR 465.60
  • EUR 4664.40
  • EUR 1278.00
  • EUR 601.20
  • EUR 284.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a). This antibody is labeled with APC.

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin)
20-abx272570
  • EUR 543.60
  • EUR 292.80
  • EUR 1579.20
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin)
20-abx303607
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

P53 And DNA Damage Regulated 1 (PDRG1) Antibody (Biotin)
20-abx311437
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Growth Arrest And DNA Damage Inducible Protein Gamma (GADD45g) Polyclonal Antibody (Mouse), APC
4-PAL536Mu01-APC
  • EUR 448.80
  • EUR 4426.80
  • EUR 1219.20
  • EUR 577.20
  • EUR 278.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Growth Arrest And DNA Damage Inducible Protein Gamma (GADD45g). This antibody is labeled with APC.

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (HRP)
20-abx316282
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (RPE)
abx444286-100ug 100 ug
EUR 661.2

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (HRP)
abx443443-100ug 100 ug
EUR 644.4

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ALP)
abx442321-100ug 100 ug
EUR 661.2

Vaccination with Messenger RNA: A Promising Alternative to DNA Vaccination

  • The first proof-of-concept studies about the feasibility of genetic vaccines were published over three decades ago, opening the way for future development. The idea of nonviral antigen delivery had multiple advantages over the traditional live or inactivated pathogen-based vaccines, but a great deal of effort had to be invested to turn the idea of genetic vaccination into reality.
  • Although early proof-of-concept studies were groundbreaking, they also showed that numerous aspects of genetic vaccines needed to be improved. Until the early 2000s, the vast majority of effort was invested into the development of DNA vaccines due to the potential issues of instability and low in vivo translatability of messenger RNA (mRNA).
  • In recent years, numerous studies have demonstrated the outstanding abilities of mRNA to elicit potent immune responses against infectious pathogens and different types of cancer, making it a viable platform for vaccine development. Multiple mRNA vaccine platforms have been developed and evaluated in small and large animals and humans and the results seem to be promising. RNA-based vaccines have important advantages over other vaccine approaches including outstanding efficacy, safety, and the potential for rapid, inexpensive, and scalable production.
  • There is a substantial investment by new mRNA companies into the development of mRNA therapeutics, particularly vaccines, increasing the number of basic and translational research publications and human clinical trials underway. This review gives a broad overview about genetic vaccines and mainly focuses on the past and present of mRNA vaccines along with the future directions to bring this potent vaccine platform closer to therapeutic use.
Atypical structures of GAA/TTC trinucleotide repeats underlying Friedreich’s ataxia: DNA triplexes and RNA/DNA hybrids
Expansion of the GAA/TTC repeats in the first intron of the FXN gene causes Friedreich’s ataxia. Non-canonical structures are linked to this expansion. DNA triplexes and R-loops are believed to arrest transcription, which results in frataxin deficiency and eventual neurodegeneration.
We present a systematic in silico characterization of the possible DNA triplexes that could be assembled with GAA and TTC strands; the two hybrid duplexes [r(GAA):d(TTC) and d(GAA):r(UUC)] in an R-loop; and three hybrid triplexes that could form during bidirectional transcription when the non-template DNA strand bonds with the hybrid duplex (collapsed R-loops, where the two DNA strands remain antiparallel).
For both Y·R:Y and R·R:Y DNA triplexes, the parallel third strand orientation is more stable; both parallel and antiparallel protonated d(GA+A)·d(GAA):d(TTC) triplexes are stable. Apparent contradictions in the literature about the R·R:Y triplex stability is probably due to lack of molecular resolution, since shifting the third strand by a single nucleotide alters the stability ranking.
In the collapsed R-loops, antiparallel d(TTC+)·d(GAA):r(UUC) is unstable, while parallel d(GAA)·r(GAA):d(TTC) and d(GA+A)·r(GAA):d(TTC) are stable. In addition to providing new structural perspectives for specific therapeutic aims, our results contribute to a systematic structural basis for the emerging field of quantitative R-loop biology.

DNA / RNA Damage Antibody
abx441445-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx441726-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442007-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442850-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx443130-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx443410-100ug 100 ug
EUR 644.4

DNA / RNA Damage Antibody
abx443691-100ug 100 ug
EUR 678

DNA / RNA Damage Antibody
abx443972-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442288-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442569-100ug 100 ug
EUR 661.2

DNA Damage-Binding Protein 1 (DDB1) Antibody (Biotin)
20-abx335378
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody (Biotin)
20-abx335381
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Monoclonal antibody for DNA/RNA Damage
SMC-155C 0.025mg
EUR 228
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

Monoclonal antibody for DNA/RNA Damage
SMC-155D 0.1mg
EUR 398.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A390 0.1mg
EUR 454.8
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 390.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A488 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 488.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A565 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 565.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A594 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A633 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 633.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A655 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 655.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A680 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 680.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A700 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 700.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-ALP 0.1mg
EUR 446.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Alkaline Phosphatase.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-APC 0.1mg
EUR 452.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-APCCY7 0.1mg
EUR 540
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC/Cy7.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-BI 0.1mg
EUR 448.8
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Biotin.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY350 0.1mg
EUR 471.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 350.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY405 0.1mg
EUR 457.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 405.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY488 0.1mg
EUR 445.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 488.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY594 0.1mg
EUR 447.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY633 0.1mg
EUR 441.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 633.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-FITC 0.1mg
EUR 444
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with FITC.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-HRP 0.1mg
EUR 439.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with HRP.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-P594 0.1mg
EUR 462
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PE/ATTO 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-PCP 0.1mg
EUR 452.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PerCP.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-RPE 0.1mg
EUR 450
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with RPE.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-STR 0.1mg
EUR 451.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Streptavidin.

Monoclonal antibody for DNA/RNA Damage
SMC-155S 0.012mg
EUR 78
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

P53 And DNA Damage Regulated 1 (PDRG1) Antibody (Biotin)
20-abx311437
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin)
20-abx272570
  • EUR 543.60
  • EUR 292.80
  • EUR 1579.20
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin)
20-abx303607
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (Biotin)
20-abx316284
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (Biotin)
abx442882-100ug 100 ug
EUR 661.2

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody (Biotin)
20-abx314619
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Growth Arrest And DNA Damage-Inducible, Alpha (GADD45A) Antibody (Biotin)
20-abx303924
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Regulated Autophagy Modulator Protein 1 (DRAM1) Antibody (Biotin)
20-abx316409
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Growth Arrest And DNA Damage Inducible Protein Beta (GADD45B) Antibody (Biotin)
20-abx303927
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Growth Arrest And DNA Damage-Inducible Protein GADD45 Gamma (GADD45G) Antibody (Biotin)
20-abx303930
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Human), Biotinylated
4-PAJ282Hu01-Biotin
  • EUR 373.20
  • EUR 2952.00
  • EUR 872.40
  • EUR 457.20
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with Biotin.

DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Mouse), Biotinylated
4-PAJ282Mu01-Biotin
  • EUR 379.20
  • EUR 3031.20
  • EUR 892.80
  • EUR 464.40
  • EUR 265.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with Biotin.

Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Mouse), Biotinylated
4-PAA319Mu01-Biotin
  • EUR 358.80
  • EUR 2745.60
  • EUR 820.80
  • EUR 435.60
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with Biotin.

Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Human, Mouse), Biotinylated
4-PAA319Hu01-Biotin
  • EUR 354.00
  • EUR 2666.40
  • EUR 801.60
  • EUR 428.40
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with Biotin.

Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a) Polyclonal Antibody (Rat), Biotinylated
4-PAL534Ra01-Biotin
  • EUR 411.60
  • EUR 3489.60
  • EUR 1006.80
  • EUR 510.00
  • EUR 278.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a). This antibody is labeled with Biotin.

Growth Arrest And DNA Damage Inducible Protein Gamma (GADD45g) Polyclonal Antibody (Mouse), Biotinylated
4-PAL536Mu01-Biotin
  • EUR 398.40
  • EUR 3315.60
  • EUR 963.60
  • EUR 493.20
  • EUR 273.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Growth Arrest And DNA Damage Inducible Protein Gamma (GADD45g). This antibody is labeled with Biotin.

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx232284-100ug 100 ug
EUR 577.2

DNA Damage-Binding Protein 1 (DDB1) Antibody
20-abx333999
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody
20-abx338922
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Growth Arrest And DNA Damage Inducible Protein Beta (GADD45b) Polyclonal Antibody (Human, Mouse), Biotinylated
4-PAL535Hu01-Biotin
  • EUR 392.40
  • EUR 3220.80
  • EUR 939.60
  • EUR 483.60
  • EUR 270.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Growth Arrest And DNA Damage Inducible Protein Beta (GADD45b). This antibody is labeled with Biotin.

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx241498
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx103576
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx176186
  • EUR 1479.60
  • EUR 710.40
  • 1 mg
  • 200 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx172142
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx213754
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx332226-100ul 100 ul
EUR 510

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx326210
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx112119
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx112120
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx026524-400ul 400 ul
EUR 627.6

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx026524-80l 80 µl
EUR 343.2

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx027183-400ul 400 ul
EUR 627.6

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx027183-80l 80 µl
EUR 343.2

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx125748
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx125750
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx123209
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx129884
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx329652
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx000607
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx004988
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx301173
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
abx236289-100ug 100 ug
EUR 577.2

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
abx148746-100ug 100 ug
EUR 526.8

P53 And Dna Damage Regulated 1 (PDRG1) Antibody
20-abx114308
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx328877
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
abx340215-100ug 100 ug
EUR 469.2

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx008020
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx014692
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx301702
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a) Polyclonal Antibody (Human, Mouse), Biotinylated
4-PAL534Hu01-Biotin
  • EUR 393.60
  • EUR 3236.40
  • EUR 943.20
  • EUR 484.80
  • EUR 271.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a). This antibody is labeled with Biotin.

DNA Damage-Binding Protein 1 (DDB1) Antibody (HRP)
20-abx335376
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody (HRP)
20-abx335379
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

OxiSelect Nitrosative DNA/RNA Damage ELISA Kit (8-Nitroguanine Quantitation)
STA-825 96 assays
EUR 957.6
Description: The OxiSelect Nitrosative DNA/RNA Damage ELISA Kit is a competitive enzyme immunoassay developed for rapid detection and quantitation of 8-nitroguanine in urine, serum, or plasma samples.

OxiSelect Nitrosative DNA/RNA Damage ELISA Kit (8-Nitroguanine Quantitation)
STA-825-5 5 x 96 assays
EUR 3888
Description: The OxiSelect Nitrosative DNA/RNA Damage ELISA Kit is a competitive enzyme immunoassay developed for rapid detection and quantitation of 8-nitroguanine in urine, serum, or plasma samples.

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
20-abx316281
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
20-abx210264
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
abx235072-100ug 100 ug
EUR 661.2

Mediator of DNA Damage Checkpoint 1 (MDC1) Antibody
abx412564-01ml 0.1 ml
EUR 844.8

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
abx444922-100ug 100 ug
EUR 594

DNA Damage-Binding Protein 1 (DDB1) Antibody (FITC)
20-abx335377
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody (FITC)
20-abx335380
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
20-abx005807
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Induced Apoptosis Suppressor (DDIAS) Antibody
20-abx323435
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx232285-100ug 100 ug
EUR 610.8
corbettresearch
10 Sep

The role of active-site amino acid residues in the cleavage of DNA and RNA

By Nicolas Antibodies , Enzymes , Exosomes , Gels , PCR , Western Blot , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , No Comments

The role of active-site amino acid residues in the cleavage of DNA and RNA substrates by human apurinic/apyrimidinic endonuclease APE1

  • Background: Human apurinic/apyrimidinic endonuclease APE1 is one of participants of the DNA base excision repair pathway. APE1 processes AP-sites and many other types of DNA damage via hydrolysis of the phosphodiester bond on the 5′ side of the lesion. APE1 also acts as an endoribonuclease, i.e., can cleave undamaged RNA.
  • Methods: Using pre-steady-state kinetic analysis we examined the role of certain catalytically important amino acids in APE1 enzymatic pathway and described their involvement in the mechanism of the target nucleotide recognition.
  • Results: Comparative analysis of the cleavage efficiency of damaged DNAs containing an abasic site, 5,6-dihydrouridine, or α-anomer of adenosine as well as 3′-5′-exonuclease degradation of undamaged DNA and endonuclease hydrolysis of RNA substrates by mutant APE1 enzymes containing a substitution of an active-site amino acid residue (D210N, N212A, T268D, M270A, or D308A) was performed. Detailed pre-steady-state kinetics of conformational changes of the enzyme and of DNA substrate molecules during recognition and cleavage of the abasic site were studied.
  • Conclusions: It was revealed that substitution T268D significantly disturbed initial DNA binding, whereas Asn212 is critical for the DNA-bending stage and catalysis. Substitution D210N increased the binding efficacy and blocked the catalytic reaction, but D308A decreased the binding efficacy owing to disruption of Mg2+ coordination. Finally, the substitution of Met270 also destabilized the enzyme-substrate complex but did not affect the catalytic reaction.
General significance: It was found that the tested substitutions of the active-site amino acid residues affected different stages of the complex formation process as well as the catalytic reaction.
corbettresearch

corbettresearch

One-4-All Genomic DNA Miniprep Kit
BS88505 250preps
EUR 393.55

Zenoquick RNA Miniprep Kit
Z5005-050 50 preps
EUR 343.2

Zenoquick RNA Miniprep Kit
Z5005-200 4x50 preps
EUR 1016.4

EZ-10 DNAaway RNA Miniprep Kit
BS88133 50Preps
EUR 155.92

EZ-10 DNAaway RNA Miniprep Kit
BS88136 250preps
EUR 455.68

Zenoquick Plant RNA Miniprep Kit
Z5016-050 50 prep
EUR 343.2

ApexPrep DNA Plasmid Miniprep Kit
A5001-300 300 tests
EUR 338.4

ApexPrep DNA Plasmid Miniprep Kit
A5001-50 50 tests
EUR 115.2

EZ-10 Spin Column Total RNA Miniprep Kit
BS1361(SK8655) 50Preps
EUR 112.98

EZ-10 Spin Column Blood RNA Miniprep Kit
BS82313 50Preps
EUR 128.51

EZ-10 Spin Column Plant RNA Miniprep Kit
BS82314 50Preps
EUR 128.51

EZ-10 Spin Column Fungal RNA Miniprep Kit
BS91915 50Preps
EUR 128.51

96-Well Plate Viral DNA Miniprep Kit
VT92032 2XPlates, 192prep
EUR 495.86

96-Well Plate DNA Cleanup Miniprep Kit
BS369 5XPlates, 480prep
EUR 300.37

96-Well Plate DNA Cleanup Miniprep Kit
BS3692 2xPlates, 192prep
EUR 186.19

96-Well Plate Plasmid DNA Miniprep Kit
BS415 5XPlates, 480prep
EUR 300.37

96-Well Plate Plasmid DNA Miniprep Kit
BS4152 2XPlates, 192prep
EUR 186.19

EZ-10 Spin Column Soil DNA Miniprep Kit
ST82316 50Preps
EUR 98.36

EZ-10 Spin Column Viral DNA Miniprep Kit
VT81812 50Preps
EUR 268.8

EZ-10 Spin Column Viral DNA Miniprep Kit
VT81813 250preps
EUR 1011.6

EZ-10 Spin Column Animal Total RNA Miniprep Kit
BS82312 50Preps
EUR 116.64

EZ-10 Spin Column Animal Total RNA Miniprep Kit
BS82322 250preps
EUR 298.55

EZ-10 Total RNA Miniprep Kit (with Proteinase K)
BS88583 50Preps
EUR 128.51

96 Well Plate Blood Genomic DNA Miniprep Kit
BT92031 2Plates, 192prep
EUR 210.85

96 Well Plate Blood Genomic DNA Miniprep Kit
BT92032 5Plates, 480prep
EUR 389.9

EZ-10 Spin Column DNA Cleanup Miniprep Kit
BS367 50Preps
EUR 91.97

EZ-10 Spin Column DNA Cleanup Miniprep Kit
BS368 100preps
EUR 114.82

EZ-10 Spin Column Plasmid DNA Miniprep Kit
BS413 50Preps
EUR 91.97
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