Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated

corbettresearch
10 Sep

Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated

By Nicolas Antibodies , Enzymes , Exosomes , Gels , PCR , Western Blot , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , No Comments

Cell Cycle Checkpoints Cooperate to Suppress DNA– and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses

  • The DNA-dependent pattern recognition receptor, cGAS (cyclic GMP-AMP synthase), mediates communication between the DNA damage and the immune responses. Mitotic chromosome missegregation stimulates cGAS activity; however, it is unclear whether progression through mitosis is required for cancercell-intrinsic activation of anti-tumor immune responses.
  • Moreover, it is unknown whether cell cycle checkpoint disruption can restore responses in cancer cells that are recalcitrant to DNAdamage-induced inflammation. Here, we demonstrate that prolonged cell cycle arrest at the G2-mitosis boundary from either excessive DNA damage or CDK1 inhibition prevents inflammatory-stimulated gene expression and immune-mediated destruction of distal tumors. Remarkably, DNAdamage-induced inflammatory signaling is restored in a RIG-I-dependent manner upon concomitant disruption of p53 and the G2 checkpoint.
  • These findings link aberrant cell progression and p53 loss to an expanded spectrum of damage-associated molecular pattern recognition and have implications for the design of rational approaches to augment anti-tumor immune responses.
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OxiSelect Oxidative RNA Damage ELISA Kit (8-OHG Quantitation), Trial Size
STA-325-T 32 assays
EUR 609.6
Description: Recently oxidative RNA damage has been described in conjunction with a wide variety of neurological diseases including Alzheimer?s disease, Parkinson?s disease, Dementia with Lewy Bodies, prion disease, and subacute sclerosing panencephalitis. We have developed an easy-to-use ELISA for the detection of the most common marker of RNA damage: 8-hydroxyguanosine (8-OHG).

OxiSelect Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation) (1 plate)
STA-320 96 assays
EUR 1152
Description: Among numerous types of oxidative DNA damage, 8-hydroxydeoxyguanosine (8-OHdG) is a ubiquitous marker of oxidative stress. 8-OHdG, one of the byproducts of oxidative DNA damage, is physiologically formed and enhanced by chemical carcinogens. Our OxiSelect Oxidative DNA Damage ELISA Kit (8-hydroxydeoxyguanosine assay) provides a powerful method for rapid, sensitive quantitation of 8-OHdG in DNA samples.

OxiSelect Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation) (5 plates)
STA-320-5 5 x 96 assays
EUR 4743.6
Description: Among numerous types of oxidative DNA damage, 8-hydroxydeoxyguanosine (8-OHdG) is a ubiquitous marker of oxidative stress. 8-OHdG, one of the byproducts of oxidative DNA damage, is physiologically formed and enhanced by chemical carcinogens. Our OxiSelect Oxidative DNA Damage ELISA Kit (8-hydroxydeoxyguanosine assay) provides a powerful method for rapid, sensitive quantitation of 8-OHdG in DNA samples.

OxiSelect Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation), Trial Size
STA-320-T 32 assays
EUR 609.6
Description: Among numerous types of oxidative DNA damage, 8-hydroxydeoxyguanosine (8-OHdG) is a ubiquitous marker of oxidative stress. 8-OHdG, one of the byproducts of oxidative DNA damage, is physiologically formed and enhanced by chemical carcinogens. Our OxiSelect Oxidative DNA Damage ELISA Kit (8-hydroxydeoxyguanosine assay) provides a powerful method for rapid, sensitive quantitation of 8-OHdG in DNA samples.

DNA / RNA Damage Antibody
abx440040-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx440321-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx440602-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx440883-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx441164-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx441445-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx441726-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442007-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx444253-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx444534-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
20-abx444884
  • EUR 594.00
  • EUR 393.60
  • 100 ug
  • 25 ug

DNA / RNA Damage Antibody
abx442288-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442569-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442850-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx443130-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx443410-100ug 100 ug
EUR 644.4

DNA / RNA Damage Antibody
abx443691-100ug 100 ug
EUR 678

DNA / RNA Damage Antibody
abx443972-100ug 100 ug
EUR 661.2

DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody
20-abx320325
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody
20-abx321453
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody
20-abx005629
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody
abx148136-100ug 100 ug
EUR 526.8

Monoclonal antibody for DNA/RNA Damage
SMC-155C 0.025mg
EUR 228
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

Monoclonal antibody for DNA/RNA Damage
SMC-155D 0.1mg
EUR 398.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A390 0.1mg
EUR 454.8
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 390.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A488 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 488.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A565 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 565.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A594 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A633 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 633.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A655 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 655.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A680 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 680.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A700 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 700.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-ALP 0.1mg
EUR 446.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Alkaline Phosphatase.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-APC 0.1mg
EUR 452.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-APCCY7 0.1mg
EUR 540
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC/Cy7.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-BI 0.1mg
EUR 448.8
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Biotin.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY350 0.1mg
EUR 471.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 350.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY405 0.1mg
EUR 457.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 405.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY488 0.1mg
EUR 445.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 488.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY594 0.1mg
EUR 447.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY633 0.1mg
EUR 441.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 633.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-FITC 0.1mg
EUR 444
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with FITC.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-HRP 0.1mg
EUR 439.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with HRP.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-P594 0.1mg
EUR 462
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PE/ATTO 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-PCP 0.1mg
EUR 452.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PerCP.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-RPE 0.1mg
EUR 450
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with RPE.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-STR 0.1mg
EUR 451.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Streptavidin.

Monoclonal antibody for DNA/RNA Damage
SMC-155S 0.012mg
EUR 78
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

Oxidative-Stress Responsive 1 (OXSR1) Antibody
20-abx114290
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody
abx236027-100ug 100 ug
EUR 610.8

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody
20-abx114289
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody
abx146030-100ug 100 ug
EUR 469.2

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody
20-abx173928
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody
20-abx128290
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody
abx029975-400ul 400 ul
EUR 627.6

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody
abx029975-80l 80 µl
EUR 343.2

Thiol Oxidative Stress Assay
1021 1 kit
EUR 460.8

Human Oxidative Stress-Responsive 1 Protein (OXSR1) Antibody
33219-05111 150 ug
EUR 313.2

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody
abx122927-100ug 100 ug
EUR 469.2

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody
20-abx302885
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Recombinant Human DNA oxidative demethylase ALKBH2 Protein, GST, E.coli-10ug
QP7771-ec-10ug 10ug
EUR 240

Recombinant Human DNA oxidative demethylase ALKBH2 Protein, GST, E.coli-1mg
QP7771-ec-1mg 1mg
EUR 1958.4

Recombinant Human DNA oxidative demethylase ALKBH2 Protein, GST, E.coli-50ug
QP7771-ec-50ug 50ug
EUR 315.6

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (HRP)
20-abx312498
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (FITC)
20-abx312499
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Recombinant Human DNA oxidative demethylase ALKBH2 Protein, GST, E.coli-100ug
QP7771-ec-100ug 100ug
EUR 489.6

Recombinant Human DNA oxidative demethylase ALKBH2 Protein, GST, E.coli-200ug
QP7771-ec-200ug 200ug
EUR 760.8

Recombinant Human DNA oxidative demethylase ALKBH2 Protein, GST, E.coli-500ug
QP7771-ec-500ug 500ug
EUR 1272

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (Biotin)
20-abx312500
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Oxidative Stress-Responsive Serine-Rich Protein 1 (OSER1) Antibody
20-abx318659
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Rat Oxidative Stress Primer Library
ROSL-I 1 set
EUR 657.6

Mouse Oxidative Stress Primer Library
MOSL-I 1 set
EUR 657.6

Human Oxidative Stress Primer Library
HOSL-I 1 set
EUR 540

Human Oxidative Stress-Responsive 1 Protein (OXSR1) Antibody (Biotin Conjugate)
33219-05121 150 ug
EUR 442.8

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Polyclonal Antibody (Human)
4-PAG202Hu01
  • EUR 296.40
  • EUR 3012.00
  • EUR 750.00
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1)

TBARS/Malondialdehyde Oxidative Stress Assay
1020 1 kit
EUR 373.2

8-isoprostane oxidative stress ELISA Kit
8iso1 1 Kit
EUR 368.4

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Polyclonal Antibody (Human), APC
4-PAG202Hu01-APC
  • EUR 414.00
  • EUR 3930.00
  • EUR 1094.40
  • EUR 528.00
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1). This antibody is labeled with APC.

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Polyclonal Antibody (Human), Cy3
4-PAG202Hu01-Cy3
  • EUR 502.80
  • EUR 5190.00
  • EUR 1410.00
  • EUR 654.00
  • EUR 301.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1). This antibody is labeled with Cy3.

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Polyclonal Antibody (Human), HRP
4-PAG202Hu01-HRP
  • EUR 379.20
  • EUR 3426.00
  • EUR 968.40
  • EUR 477.60
  • EUR 247.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1). This antibody is labeled with HRP.

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Polyclonal Antibody (Human), PE
4-PAG202Hu01-PE
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1). This antibody is labeled with PE.

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Polyclonal Antibody (Human), FITC
4-PAG202Hu01-FITC
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1). This antibody is labeled with FITC.

Human Oxidative Stress-Responsive 1 Protein (OXSR1) AssayLite Antibody (RPE Conjugate)
33219-05151 150 ug
EUR 513.6

Human Oxidative Stress-Responsive 1 Protein (OXSR1) AssayLite Antibody (APC Conjugate)
33219-05161 150 ug
EUR 513.6

Human Oxidative Stress-Responsive 1 Protein (OXSR1) AssayLite Antibody (FITC Conjugate)
33219-05141 150 ug
EUR 513.6

Human Oxidative Stress-Responsive 1 Protein (OXSR1) AssayLite Antibody (PerCP Conjugate)
33219-05171 150 ug
EUR 565.2

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Polyclonal Antibody (Human), APC-Cy7
4-PAG202Hu01-APC-Cy7
  • EUR 685.20
  • EUR 7716.00
  • EUR 2046.00
  • EUR 912.00
  • EUR 382.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1). This antibody is labeled with APC-Cy7.

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Polyclonal Antibody (Human), Biotinylated
4-PAG202Hu01-Biotin
  • EUR 373.20
  • EUR 2952.00
  • EUR 872.40
  • EUR 457.20
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1). This antibody is labeled with Biotin.

Human Oxidative Stress-Responsive 1 Protein (OXSR1) AssayLite Antibody (FITC, RPE, APC, PerCP Conjugate)
33219-05181 1 x 75 ug, 3 x 30 ug
EUR 702

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx232284-100ug 100 ug
EUR 577.2

DNA Damage-Binding Protein 1 (DDB1) Antibody
20-abx333999
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody
20-abx338922
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

OxiSelect Nitrosative DNA/RNA Damage ELISA Kit (8-Nitroguanine Quantitation)
STA-825 96 assays
EUR 957.6
Description: The OxiSelect Nitrosative DNA/RNA Damage ELISA Kit is a competitive enzyme immunoassay developed for rapid detection and quantitation of 8-nitroguanine in urine, serum, or plasma samples.

OxiSelect Nitrosative DNA/RNA Damage ELISA Kit (8-Nitroguanine Quantitation)
STA-825-5 5 x 96 assays
EUR 3888
Description: The OxiSelect Nitrosative DNA/RNA Damage ELISA Kit is a competitive enzyme immunoassay developed for rapid detection and quantitation of 8-nitroguanine in urine, serum, or plasma samples.

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx213754
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx172142
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx326210
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx000607
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx004988
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx103576
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx112119
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx112120
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx176186
  • EUR 1479.60
  • EUR 710.40
  • 1 mg
  • 200 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx125748
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx125750
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx241498
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx123209
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx129884
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx301173
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx026524-400ul 400 ul
EUR 627.6

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx026524-80l 80 µl
EUR 343.2

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx027183-400ul 400 ul
EUR 627.6

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx027183-80l 80 µl
EUR 343.2

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx332226-100ul 100 ul
EUR 510

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx329652
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

P53 And Dna Damage Regulated 1 (PDRG1) Antibody
20-abx114308
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx328877
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx014692
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx008020
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
abx236289-100ug 100 ug
EUR 577.2

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
abx148746-100ug 100 ug
EUR 526.8

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx301702
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
abx340215-100ug 100 ug
EUR 469.2

OXSR1 Oxidative Stress Responsive 1 Human Recombinant Protein
PROTO95747 Regular: 20ug
EUR 380.4
Description: OXSR1 Human Recombinant produced in E. coli is a single polypeptide chain containing 550 amino acids (1-527) and having a molecular mass of 60.4kDa.;OXSR1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Recombinant Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1)
4-RPG202Hu01
  • EUR 603.84
  • EUR 285.60
  • EUR 1934.40
  • EUR 724.80
  • EUR 1329.60
  • EUR 480.00
  • EUR 4656.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Oxidative Stress Induced Growth Inhibitor 1 expressed in: E.coli

DNA Damage-Binding Protein 1 (DDB1) Antibody (HRP)
20-abx335376
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody (HRP)
20-abx335379
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
abx235072-100ug 100 ug
EUR 661.2

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
20-abx316281
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 1 (DDB1) Antibody (FITC)
20-abx335377
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody (FITC)
20-abx335380
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
20-abx005807
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Mediator of DNA Damage Checkpoint 1 (MDC1) Antibody
abx412564-01ml 0.1 ml
EUR 844.8

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
20-abx210264
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
abx444922-100ug 100 ug
EUR 594

Human Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Protein
20-abx167104
  • EUR 844.80
  • EUR 343.20
  • EUR 2598.00
  • EUR 994.80
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Induced Apoptosis Suppressor (DDIAS) Antibody
20-abx323435
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Human Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) CLIA Kit
20-abx495130
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx232285-100ug 100 ug
EUR 610.8

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
abx232286-100ug 100 ug
EUR 577.2

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
20-abx225140
  • EUR 444.00
  • EUR 727.20
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx219380-100ug 100 ug
EUR 526.8

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
20-abx141699
  • EUR 444.00
  • EUR 727.20
  • EUR 360.00
  • 100 ul
  • 200 ul
  • 50 ul

DNA Damage-Binding Protein 1 (DDB1) Antibody (Biotin)
20-abx335378
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody (Biotin)
20-abx335381
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
20-abx001528
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
20-abx002127
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx412503-01mg 0.1 mg
EUR 961.2

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
20-abx111958
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
20-abx111959
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

A G-quadruplex-forming RNA aptamer binds to the MTG8 TAFH domain and dissociates the leukemic AML1-MTG8 fusion protein from DNA

MTG8 (RUNX1T1) is a fusion partner of AML1 (RUNX1) in the leukemic chromosome translocation t(8;21). The AML1-MTG8 fusion gene encodes a chimeric transcription factor. One of the highly conserved domains of MTG8 is TAFH which possesses homology with human TAF4 [TATA-box binding protein (TBP)-associated factor].
To obtain specific inhibitors of the AML1-MTG8 fusion protein, we isolated RNA aptamers against the MTG8 TAFH domain using Systematic Evolution of Ligands by EXponential enrichment (SELEX). All TAF aptamers contained guanine-rich sequences. Analyses of a TAF aptamer by NMR, CD and mutagenesis revealed that it forms a parallel G-quadruplex structure in the presence of K+ .
Furthermore, the aptamer could bind to the AML1-MTG8 fusion protein and dissociate the AML1-MTG8/DNA complex, suggesting that it can inhibit the dominant negative effects of AML1-MTG8 against normal AML1 function and serve as a potential therapeutic agent for leukemia.

DNA–RNA Heteroduplex Oligonucleotide for Highly Efficient Gene Silencing

Heteroduplex oligonucleotides (HDOs) were a novel type of nucleic acid drugs based on an antisense oligonucleotide (ASO) strand and its complementary RNA (cRNA ) strand.
HDOs were originally designed to improve the properties of RNase H-dependent ASOs and we reported in our first paper that HDOs conjugated with an α-tocopherol ligand (Toc-HDO ) based on a gapmer ASO showed 20 times higher silencing effect to liver apolipoprotein B (apoB) mRNA in vivo than the parent ASO.
Thereafter the HDO strategy was found to be also effective for improving the properties of ASOs modulating blood-brain barrier function and ASO antimiRs which are RNase H-independent ASOs. Therefore, the HDO strategy has been shown to be versatile technology platform to develop effective nucleic acid drugs.

Site-selective RNA Functionalization via DNA-induced Structure

Methods for RNA functionalization at specific sites are in high demand, but remain a challenge, particularly for RNAs produced by transcription rather than by total synthesis. Recent studies have described acylimidazole reagents that react in high yields at 2′-OH groups stochastically at non-base-paired regions, covering much of the RNA in scattered acyl esters.
Localized reactions, if possible, could prove useful in many applications, providing functional handles at specific sites and sequences of the biopolymer. Here we describe a DNA-directed strategy for in vitro functionalization of RNA at site-localized 2′-OH groups. The method, RNA Acylation at Induced Loops (RAIL), utilizes complementary helper DNA oligonucleotides that expose gaps or loops at selected positions while protecting the remainder in DNA-RNA duplexes.
Reaction with an acylimidazole reagent is then carried out, providing high yields of 2′-OH conjugation at predetermined sites. Experiments reveal optimal helper oligodeoxynucleotide designs and conditions for the reaction, and tests of the approach are carried out to control localized ribozyme activities and to label RNAs with dual-color fluorescent dyes. The RAIL approach offers a simple and novel strategy for site-specific labeling and control of RNAs, potentially of any length and origin.

Optimization of a Method for the Simultaneous Extraction of Polar and Non-Polar Oxylipin Metabolites, DNA, RNA, Small RNA, and Protein from a Single Small Tissue Sample

A more comprehensive picture of tissue biology can be obtained through the application and integration of multiple omic technologies. However, the common challenge in working with a precious sample is having a sample too small to separately extract analytes of interest for each experiment. Considering the high heterogeneity that can be present in a single tissue sample, extracting all biomolecules from a single and undivided tissue is preferable because it allows direct comparison of results.
Here, we combined a modified Folch extraction method with DNA, RNA, small RNA, and protein extraction using two commercial kits, which allowed us to extract polar metabolites and non-polar oxylipin metabolites, DNA, RNA, small RNA, and protein simultaneously from a small tissue sample. The method was validated in terms of quantity and quality of analytes for downstream analyses.

DNA / RNA Damage Antibody
abx441726-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442007-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx444253-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx444534-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
20-abx444884
  • EUR 594.00
  • EUR 393.60
  • 100 ug
  • 25 ug

DNA / RNA Damage Antibody
abx442288-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442569-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx442850-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx443130-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody
abx443410-100ug 100 ug
EUR 644.4

DNA / RNA Damage Antibody
abx443691-100ug 100 ug
EUR 678

DNA / RNA Damage Antibody
abx443972-100ug 100 ug
EUR 661.2

Monoclonal antibody for DNA/RNA Damage
SMC-155C 0.025mg
EUR 228
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

Monoclonal antibody for DNA/RNA Damage
SMC-155D 0.1mg
EUR 398.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A390 0.1mg
EUR 454.8
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 390.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A488 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 488.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A565 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 565.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A594 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A633 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 633.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A655 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 655.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A680 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 680.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-A700 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 700.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-ALP 0.1mg
EUR 446.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Alkaline Phosphatase.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-APC 0.1mg
EUR 452.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-APCCY7 0.1mg
EUR 540
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC/Cy7.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-BI 0.1mg
EUR 448.8
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Biotin.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY350 0.1mg
EUR 471.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 350.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY405 0.1mg
EUR 457.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 405.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY488 0.1mg
EUR 445.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 488.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY594 0.1mg
EUR 447.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-DY633 0.1mg
EUR 441.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 633.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-FITC 0.1mg
EUR 444
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with FITC.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-HRP 0.1mg
EUR 439.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with HRP.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-P594 0.1mg
EUR 462
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PE/ATTO 594.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-PCP 0.1mg
EUR 452.4
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PerCP.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-RPE 0.1mg
EUR 450
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with RPE.

Monoclonal antibody for DNA/RNA Damage
SMC-155D-STR 0.1mg
EUR 451.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Streptavidin.

Monoclonal antibody for DNA/RNA Damage
SMC-155S 0.012mg
EUR 78
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

DNA Damage-Binding Protein 1 (DDB1) Antibody
abx232284-100ug 100 ug
EUR 577.2

DNA Damage-Binding Protein 1 (DDB1) Antibody
20-abx333999
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody
20-abx338922
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx213754
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx172142
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx326210
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx000607
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx004988
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx103576
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx112119
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx112120
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx176186
  • EUR 1479.60
  • EUR 710.40
  • 1 mg
  • 200 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx125748
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx125750
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx241498
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody
20-abx123209
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx129884
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx301173
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx026524-400ul 400 ul
EUR 627.6

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx026524-80l 80 µl
EUR 343.2

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx027183-400ul 400 ul
EUR 627.6

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx027183-80l 80 µl
EUR 343.2

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
abx332226-100ul 100 ul
EUR 510

DNA Damage Inducible Transcript 3 (DDIT3) Antibody
20-abx329652
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

P53 And Dna Damage Regulated 1 (PDRG1) Antibody
20-abx114308
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx328877
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx014692
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx008020
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
abx236289-100ug 100 ug
EUR 577.2

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
abx148746-100ug 100 ug
EUR 526.8

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
20-abx301702
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

P53 And DNA Damage Regulated 1 (PDRG1) Antibody
abx340215-100ug 100 ug
EUR 469.2

OxiSelect Nitrosative DNA/RNA Damage ELISA Kit (8-Nitroguanine Quantitation)
STA-825 96 assays
EUR 957.6
Description: The OxiSelect Nitrosative DNA/RNA Damage ELISA Kit is a competitive enzyme immunoassay developed for rapid detection and quantitation of 8-nitroguanine in urine, serum, or plasma samples.

OxiSelect Nitrosative DNA/RNA Damage ELISA Kit (8-Nitroguanine Quantitation)
STA-825-5 5 x 96 assays
EUR 3888
Description: The OxiSelect Nitrosative DNA/RNA Damage ELISA Kit is a competitive enzyme immunoassay developed for rapid detection and quantitation of 8-nitroguanine in urine, serum, or plasma samples.

DNA Damage-Binding Protein 1 (DDB1) Antibody (HRP)
20-abx335376
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody (HRP)
20-abx335379
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
abx235072-100ug 100 ug
EUR 661.2

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
20-abx316281
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 1 (DDB1) Antibody (FITC)
20-abx335377
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody (FITC)
20-abx335380
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
20-abx005807
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Mediator of DNA Damage Checkpoint 1 (MDC1) Antibody
abx412564-01ml 0.1 ml
EUR 844.8

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
20-abx210264
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
abx444922-100ug 100 ug
EUR 594

DNA Damage Induced Apoptosis Suppressor (DDIAS) Antibody
20-abx323435
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx232285-100ug 100 ug
EUR 610.8

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
abx232286-100ug 100 ug
EUR 577.2

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
20-abx225140
  • EUR 444.00
  • EUR 727.20
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx219380-100ug 100 ug
EUR 526.8

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
20-abx141699
  • EUR 444.00
  • EUR 727.20
  • EUR 360.00
  • 100 ul
  • 200 ul
  • 50 ul

DNA Damage-Binding Protein 1 (DDB1) Antibody (Biotin)
20-abx335378
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody (Biotin)
20-abx335381
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
20-abx001528
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
20-abx002127
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx412503-01mg 0.1 mg
EUR 961.2

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
20-abx111958
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
20-abx111959
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
20-abx128508
  • EUR 477.60
  • EUR 159.60
  • EUR 1312.80
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
20-abx242438
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
20-abx242444
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx159468-100ul 100 ul
EUR 560.4

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx159469-100ul 100 ul
EUR 560.4

Damage Specific DNA Binding Protein 2 (DDB2) Antibody
20-abx130944
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Damage Specific DNA Binding Protein 1 (DDB1) Antibody
abx432057-200ul 200 ul
EUR 460.8

P53 And DNA Damage Regulated 1 (PDRG1) Antibody (HRP)
20-abx311435
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (HRP)
20-abx303605
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (FITC)
20-abx303606
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

P53 And DNA Damage Regulated 1 (PDRG1) Antibody (FITC)
20-abx311436
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

EpiQuik Nitrosative (8-Nitroguanine) DNA/RNA Damage Quantification Kit (Colorimetric)
P-6009
  • EUR 486.20
  • EUR 775.50
  • 48 Assays
  • 96 Assays

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody
20-abx213755
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody
20-abx213756
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody
abx140150-01mg 0.1 mg
EUR 510

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody
20-abx112121
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody
20-abx302163
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin)
20-abx272570
  • EUR 543.60
  • EUR 292.80
  • EUR 1579.20
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin)
20-abx303607
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

P53 And DNA Damage Regulated 1 (PDRG1) Antibody (Biotin)
20-abx311437
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (HRP)
20-abx316282
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (RPE)
abx444286-100ug 100 ug
EUR 661.2

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ALP)
abx442321-100ug 100 ug
EUR 661.2

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (APC)
abx442602-100ug 100 ug
EUR 661.2

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (HRP)
abx443443-100ug 100 ug
EUR 644.4

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (FITC)
20-abx316283