Tag Archive : antibodies lifespan

corbettresearch

G-quadruplex DNA and RNA: Their roles in regulation of DNA replication and other biological functions

  • G-quadruplex is one of the best-studied non-B type DNA that is now known to be prevalently present in the genomes of almost all the biological species. Recent studies reveal roles of G-quadruplex (G4) structures in various nucleic acids and chromosome transactions.
  • In this short article, we will first describe recent findings on the roles of G4 in regulation of DNA replication. G4 is involved in regulation of spatio-temporal regulation of DNA replication through interaction with a specific binding protein, Rif1. This regulation is at least partially mediated by generation of specific chromatin architecture through Rif1-G4 interactions.
  • We will also describe recent studies showing the potential roles of G4 in initiation of DNA replication. Next, we will present showcases of highly diversified roles of DNA G4 and RNA G4 in regulation of nucleic acid and chromosome functions. Finally, we will discuss how the formation of cellular G4 could be regulated.
corbettresearch

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DNA / RNA Damage Antibody

abx440602-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx440883-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx441164-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx441445-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx441726-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442007-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442288-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442569-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442850-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx443130-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx443410-100ug 100 ug
EUR 644.4

DNA / RNA Damage Antibody

abx443691-100ug 100 ug
EUR 678

DNA / RNA Damage Antibody

20-abx444884
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  • 100 ug
  • 25 ug

DNA / RNA Damage Antibody

abx443972-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx444253-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx444534-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx444884-100l 100 µl
EUR 337.5

DNA / RNA Damage Antibody (PE)

abx444253-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (HRP)

abx443410-100g 100 µg
EUR 562.5

DNA / RNA Damage Antibody (FITC)

abx443130-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (PerCP)

abx443972-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (Biotin)

abx442850-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (ATTO594)

abx440883-100g 100 µg
EUR 587.5

DNA / RNA Damage Antibody (ATTO390)

abx440040-200g 200 µg
EUR 587.5

DNA / RNA Damage Antibody (ATTO488)

abx440321-100g 100 µg
EUR 587.5

DNA/RNA Damage Antibody, Clone 15A3

SMC-155C 0.025mg
EUR 144
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

DNA/RNA Damage Antibody, Clone 15A3

SMC-155D 0.1mg
EUR 306
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

DNA/RNA Damage Antibody, Clone 15A3

SMC-155S 0.012mg
EUR 44
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

OASE00080-25UG - DNA/RNA Damage Antibody

OASE00080-25UG 25ug
EUR 199

OASE00081-100UG - DNA/RNA Damage Antibody

OASE00081-100UG 100ug
EUR 399

DNA/RNA Damage Antibody, Clone 15A3: HRP

SMC-155D-HRP 0.1mg
EUR 345
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with HRP.

DNA/RNA Damage Antibody, Clone 15A3: RPE

SMC-155D-RPE 0.1mg
EUR 355
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with RPE.

DNA/RNA Damage Antibody, Clone 15A3: FITC

SMC-155D-FITC 0.1mg
EUR 350
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with FITC.

DNA/RNA Damage Antibody, Clone 15A3: PerCP

SMC-155D-PCP 0.1mg
EUR 358
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PerCP.

DNA/RNA Damage Antibody, Clone 15A3: Biotin

SMC-155D-BI 0.1mg
EUR 354
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Biotin.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A565 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 565.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A633 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 633.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A655 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 655.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A680 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 680.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A700 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 700.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-APCCY7 0.1mg
EUR 540
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC/Cy7.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY350 0.1mg
EUR 471.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 350.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY405 0.1mg
EUR 457.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 405.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY488 0.1mg
EUR 445.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 488.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY594 0.1mg
EUR 447.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 594.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY633 0.1mg
EUR 441.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 633.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-P594 0.1mg
EUR 462
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PE/ATTO 594.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-STR 0.1mg
EUR 451.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Streptavidin.

DNA/RNA Damage Antibody, Clone 15A3: ATTO 390

SMC-155D-A390 0.1mg
EUR 360
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 390.

DNA/RNA Damage Antibody, Clone 15A3: ATTO 488

SMC-155D-A488 0.1mg
EUR 359
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 488.

DNA/RNA Damage Antibody, Clone 15A3: ATTO 594

SMC-155D-A594 0.1mg
EUR 359
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 594.

DNA/RNA Damage Antibody, Clone 15A3: Alkaline Phosphatase

SMC-155D-ALP 0.1mg
EUR 352
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Alkaline Phosphatase.

Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody

12503 100ug
EUR 230

Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody

12503-100 100ug
EUR 230

Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody

12503-500 500ug
EUR 460

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (APC)

abx442602-100ug 100 ug
EUR 661.2

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (APC)

abx442602-100g 100 µg
EUR 575

Anti-8-hydroxyguanosine DNA/RNA Oxidative Damage Mouse Monoclonal Antibody

12501 100ug
EUR 380

DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Human), APC

4-PAJ282Hu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with APC.

DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Mouse), APC

4-PAJ282Mu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with APC.

Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Mouse), APC

4-PAA319Mu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with APC.

DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Human), APC-Cy7

4-PAJ282Hu01-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with APC-Cy7.

DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Mouse), APC-Cy7

4-PAJ282Mu01-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with APC-Cy7.

Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Human, Mouse), APC

4-PAA319Hu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with APC.

Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Mouse), APC-Cy7

4-PAA319Mu01-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with APC-Cy7.

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx232284-100ug 100 ug
EUR 577.2

DNA Damage-Binding Protein 1 (DDB1) Antibody

20-abx333999
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody

20-abx338922
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody

abx001528-100l 100 µl
EUR 400

DNA Damage-Binding Protein 2 (DDB2) Antibody

abx001528-20l 20 µl
EUR 175

DNA Damage-Binding Protein 2 (DDB2) Antibody

abx001528-50l 50 µl
EUR 275

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx002127-100l 100 µl
EUR 400

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx002127-20l 20 µl
EUR 175

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx002127-50l 50 µl
EUR 275

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx159468-100g 100 µg Ask for price

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx159468-10g 10 µg
EUR 437.5

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx159468-50g 50 µg Ask for price

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx159469-100g 100 µg Ask for price

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx159469-10g 10 µg
EUR 437.5

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx159469-50g 50 µg Ask for price

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx242438-96tests 96 tests
EUR 250

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx242444-96tests 96 tests
EUR 250

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx232284-100g 100 µg
EUR 350

DNA Damage-Binding Protein 2 (DDB2) Antibody

abx338922-100l 100 µl
EUR 250

DNA Damage-Binding Protein 2 (DDB2) Antibody

abx338922-50l 50 µl
EUR 162.5

DNA damage-binding protein 2 (DDB2) Antibody

abx402261-100tests 100 tests
EUR 287.5

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx333999-100g 100 µg
EUR 362.5

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx333999-20g 20 µg
EUR 162.5

DNA Damage-Binding Protein 1 (DDB1) Antibody

abx333999-50g 50 µg
EUR 250

Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Human, Mouse), APC-Cy7

4-PAA319Hu01-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with APC-Cy7.

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

20-abx112119
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  • 150 ul
  • 50 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody

20-abx112120
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  • 150 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

20-abx103576
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

20-abx129884
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Inducible Transcript 4 (DDIT4) Antibody

20-abx123209
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  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

20-abx125748
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  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

20-abx125750
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  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx026524-400ul 400 ul
EUR 627.6

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx026524-80l 80 µl
EUR 343.2

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx027183-400ul 400 ul
EUR 627.6

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx027183-80l 80 µl
EUR 343.2

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

20-abx004988
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  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

20-abx000607
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  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Damage Inducible Transcript 4 (DDIT4) Antibody

20-abx213754
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  • 100 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

20-abx172142
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  • 1 mg
  • 200 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

20-abx176186
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  • 1 mg
  • 200 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx332226-100ul 100 ul
EUR 510

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

20-abx326210
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  • 100 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

20-abx329652
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  • 100 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

20-abx301173
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Inducible Transcript 4 (DDIT4) Antibody

20-abx241498
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  • 100 ul
  • 50 ul

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx004988-100l 100 µl
EUR 400

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx004988-20l 20 µl
EUR 175

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx004988-50l 50 µl
EUR 275

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx010557-100g 100 µg Ask for price

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx010557-10g 10 µg
EUR 350

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx010557-200g 200 µg Ask for price

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx010559-100g 100 µg
EUR 387.5

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx010559-10g 10 µg
EUR 300

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx010559-200g 200 µg Ask for price

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx000607-100l 100 µl
EUR 400

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx000607-20l 20 µl
EUR 175

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx000607-50l 50 µl
EUR 275

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx103576-100g 100 µg
EUR 750

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx103576-20g 20 µg
EUR 275

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx103576-50g 50 µg
EUR 337.5

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx129884-100l 100 µl
EUR 275

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx129884-1ml 1 ml
EUR 775

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx129884-200l 200 µl
EUR 350

DNA Damage Inducible Transcript 3 (DDIT3) Antibody

abx172142-1ml 1 ml
EUR 787.5

DNA Damage Inducible Transcript 4 (DDIT4) Antibody

abx213754-100l 100 µl
EUR 250

DNA Damage Inducible Transcript 4 (DDIT4) Antibody

abx123209-100l 100 µl
EUR 200

Vaccination with Messenger RNA: A Promising Alternative to DNA Vaccination

  • The first proof-of-concept studies about the feasibility of genetic vaccines were published over three decades ago, opening the way for future development. The idea of nonviral antigen delivery had multiple advantages over the traditional live or inactivated pathogen-based vaccines, but a great deal of effort had to be invested to turn the idea of genetic vaccination into reality.
  • Although early proof-of-concept studies were groundbreaking, they also showed that numerous aspects of genetic vaccines needed to be improved. Until the early 2000s, the vast majority of effort was invested into the development of DNA vaccines due to the potential issues of instability and low in vivo translatability of messenger RNA (mRNA).
  • In recent years, numerous studies have demonstrated the outstanding abilities of mRNA to elicit potent immune responses against infectious pathogens and different types of cancer, making it a viable platform for vaccine development. Multiple mRNA vaccine platforms have been developed and evaluated in small and large animals and humans and the results seem to be promising. RNA-based vaccines have important advantages over other vaccine approaches including outstanding efficacy, safety, and the potential for rapid, inexpensive, and scalable production.
  • There is a substantial investment by new mRNA companies into the development of mRNA therapeutics, particularly vaccines, increasing the number of basic and translational research publications and human clinical trials underway. This review gives a broad overview about genetic vaccines and mainly focuses on the past and present of mRNA vaccines along with the future directions to bring this potent vaccine platform closer to therapeutic use.
Atypical structures of GAA/TTC trinucleotide repeats underlying Friedreich’s ataxia: DNA triplexes and RNA/DNA hybrids
Expansion of the GAA/TTC repeats in the first intron of the FXN gene causes Friedreich’s ataxia. Non-canonical structures are linked to this expansion. DNA triplexes and R-loops are believed to arrest transcription, which results in frataxin deficiency and eventual neurodegeneration.
We present a systematic in silico characterization of the possible DNA triplexes that could be assembled with GAA and TTC strands; the two hybrid duplexes [r(GAA):d(TTC) and d(GAA):r(UUC)] in an R-loop; and three hybrid triplexes that could form during bidirectional transcription when the non-template DNA strand bonds with the hybrid duplex (collapsed R-loops, where the two DNA strands remain antiparallel).
For both Y·R:Y and R·R:Y DNA triplexes, the parallel third strand orientation is more stable; both parallel and antiparallel protonated d(GA+A)·d(GAA):d(TTC) triplexes are stable. Apparent contradictions in the literature about the R·R:Y triplex stability is probably due to lack of molecular resolution, since shifting the third strand by a single nucleotide alters the stability ranking.
In the collapsed R-loops, antiparallel d(TTC+)·d(GAA):r(UUC) is unstable, while parallel d(GAA)·r(GAA):d(TTC) and d(GA+A)·r(GAA):d(TTC) are stable. In addition to providing new structural perspectives for specific therapeutic aims, our results contribute to a systematic structural basis for the emerging field of quantitative R-loop biology.

DNA / RNA Damage Antibody

abx441726-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442007-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442288-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442569-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442850-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx443130-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx443410-100ug 100 ug
EUR 644.4

DNA / RNA Damage Antibody

abx443691-100ug 100 ug
EUR 678

DNA / RNA Damage Antibody

20-abx444884
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  • 100 ug
  • 25 ug

DNA / RNA Damage Antibody

abx443972-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx444253-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx444534-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx444884-100l 100 µl
EUR 337.5

DNA / RNA Damage Antibody (PE)

abx444253-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (APC)

abx442569-100l 100 µl
EUR 575

DNA / RNA Damage Antibody (HRP)

abx443410-100g 100 µg
EUR 562.5

DNA / RNA Damage Antibody (FITC)

abx443130-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (PerCP)

abx443972-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (ATTO594)

abx440883-100g 100 µg
EUR 587.5

DNA / RNA Damage Antibody (ATTO390)

abx440040-200g 200 µg
EUR 587.5

DNA / RNA Damage Antibody (ATTO488)

abx440321-100g 100 µg
EUR 587.5

DNA/RNA Damage Antibody, Clone 15A3

SMC-155C 0.025mg
EUR 144
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

DNA/RNA Damage Antibody, Clone 15A3

SMC-155D 0.1mg
EUR 306
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

DNA/RNA Damage Antibody, Clone 15A3

SMC-155S 0.012mg
EUR 44
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

OASE00080-25UG - DNA/RNA Damage Antibody

OASE00080-25UG 25ug
EUR 199

OASE00081-100UG - DNA/RNA Damage Antibody

OASE00081-100UG 100ug
EUR 399

DNA Damage-Binding Protein 1 (DDB1) Antibody (Biotin)

20-abx335378
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 2 (DDB2) Antibody (Biotin)

20-abx335381
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage-Binding Protein 1 (DDB1) Antibody (Biotin)

abx335378-100g 100 µg
EUR 362.5

DNA Damage-Binding Protein 1 (DDB1) Antibody (Biotin)

abx335378-20g 20 µg
EUR 162.5

DNA Damage-Binding Protein 1 (DDB1) Antibody (Biotin)

abx335378-50g 50 µg
EUR 250

DNA Damage-Binding Protein 2 (DDB2) Antibody (Biotin)

abx335381-100g 100 µg
EUR 362.5

DNA Damage-Binding Protein 2 (DDB2) Antibody (Biotin)

abx335381-20g 20 µg
EUR 162.5

DNA Damage-Binding Protein 2 (DDB2) Antibody (Biotin)

abx335381-50g 50 µg
EUR 250

DNA/RNA Damage Antibody, Clone 15A3: APC

SMC-155D-APC 0.1mg
EUR 358
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC.

DNA/RNA Damage Antibody, Clone 15A3: HRP

SMC-155D-HRP 0.1mg
EUR 345
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with HRP.

DNA/RNA Damage Antibody, Clone 15A3: RPE

SMC-155D-RPE 0.1mg
EUR 355
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with RPE.

DNA/RNA Damage Antibody, Clone 15A3: FITC

SMC-155D-FITC 0.1mg
EUR 350
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with FITC.

DNA/RNA Damage Antibody, Clone 15A3: PerCP

SMC-155D-PCP 0.1mg
EUR 358
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PerCP.

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin)

20-abx272570
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin)

20-abx303607
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin)

abx303607-100g 100 µg
EUR 362.5

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin)

abx303607-20g 20 µg
EUR 162.5

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin)

abx303607-50g 50 µg
EUR 250

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin)

abx272570-1ml 1 ml
EUR 825

DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin)

abx272570-200l 200 µl
EUR 362.5

P53 And DNA Damage Regulated 1 (PDRG1) Antibody (Biotin)

20-abx311437
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

P53 And DNA Damage Regulated 1 (PDRG1) Antibody (Biotin)

abx311437-100g 100 µg
EUR 362.5

P53 And DNA Damage Regulated 1 (PDRG1) Antibody (Biotin)

abx311437-20g 20 µg
EUR 162.5

P53 And DNA Damage Regulated 1 (PDRG1) Antibody (Biotin)

abx311437-50g 50 µg
EUR 250

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A565 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 565.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A633 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 633.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A655 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 655.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A680 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 680.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A700 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 700.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-APCCY7 0.1mg
EUR 540
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC/Cy7.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY350 0.1mg
EUR 471.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 350.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY405 0.1mg
EUR 457.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 405.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY488 0.1mg
EUR 445.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 488.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY594 0.1mg
EUR 447.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 594.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY633 0.1mg
EUR 441.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 633.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-P594 0.1mg
EUR 462
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PE/ATTO 594.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-STR 0.1mg
EUR 451.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Streptavidin.

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (Biotin)

abx442882-100ug 100 ug
EUR 661.2

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (Biotin)

20-abx316284
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (Biotin)

abx442882-100g 100 µg
EUR 575

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (Biotin)

abx316284-100g 100 µg
EUR 362.5

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (Biotin)

abx316284-20g 20 µg
EUR 162.5

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (Biotin)

abx316284-50g 50 µg
EUR 250

DNA/RNA Damage Antibody, Clone 15A3: ATTO 390

SMC-155D-A390 0.1mg
EUR 360
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 390.

DNA/RNA Damage Antibody, Clone 15A3: ATTO 488

SMC-155D-A488 0.1mg
EUR 359
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 488.

DNA/RNA Damage Antibody, Clone 15A3: ATTO 594

SMC-155D-A594 0.1mg
EUR 359
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 594.

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody (Biotin)

20-abx314619
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody (Biotin)

abx314619-100g 100 µg
EUR 362.5

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody (Biotin)

abx314619-20g 20 µg
EUR 162.5

DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody (Biotin)

abx314619-50g 50 µg
EUR 250

DNA/RNA Damage Antibody, Clone 15A3: Alkaline Phosphatase

SMC-155D-ALP 0.1mg
EUR 352
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Alkaline Phosphatase.

Growth Arrest And DNA Damage-Inducible, Alpha (GADD45A) Antibody (Biotin)

20-abx303924
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Growth Arrest And DNA Damage-Inducible, Alpha (GADD45A) Antibody (Biotin)

abx303924-100g 100 µg
EUR 362.5

Growth Arrest And DNA Damage-Inducible, Alpha (GADD45A) Antibody (Biotin)

abx303924-20g 20 µg
EUR 162.5

Growth Arrest And DNA Damage-Inducible, Alpha (GADD45A) Antibody (Biotin)

abx303924-50g 50 µg
EUR 250

DNA Damage Regulated Autophagy Modulator Protein 1 (DRAM1) Antibody (Biotin)

20-abx316409
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Damage Regulated Autophagy Modulator Protein 1 (DRAM1) Antibody (Biotin)

abx316409-100g 100 µg
EUR 362.5

DNA Damage Regulated Autophagy Modulator Protein 1 (DRAM1) Antibody (Biotin)

abx316409-20g 20 µg
EUR 162.5

DNA Damage Regulated Autophagy Modulator Protein 1 (DRAM1) Antibody (Biotin)

abx316409-50g 50 µg
EUR 250

Growth Arrest And DNA Damage Inducible Protein Beta (GADD45B) Antibody (Biotin)

20-abx303927
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Growth Arrest And DNA Damage Inducible Protein Beta (GADD45B) Antibody (Biotin)

abx303927-100g 100 µg
EUR 362.5

Growth Arrest And DNA Damage Inducible Protein Beta (GADD45B) Antibody (Biotin)

abx303927-20g 20 µg
EUR 162.5

Growth Arrest And DNA Damage Inducible Protein Beta (GADD45B) Antibody (Biotin)

abx303927-50g 50 µg
EUR 250

Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody

12503 100ug
EUR 230

Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody

12503-100 100ug
EUR 230

Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody

12503-500 500ug
EUR 460

Growth Arrest And DNA Damage-Inducible Protein GADD45 Gamma (GADD45G) Antibody (Biotin)

20-abx303930
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Growth Arrest And DNA Damage-Inducible Protein GADD45 Gamma (GADD45G) Antibody (Biotin)

abx303930-100g 100 µg
EUR 362.5

Growth Arrest And DNA Damage-Inducible Protein GADD45 Gamma (GADD45G) Antibody (Biotin)

abx303930-20g 20 µg
EUR 162.5

Growth Arrest And DNA Damage-Inducible Protein GADD45 Gamma (GADD45G) Antibody (Biotin)

abx303930-50g 50 µg
EUR 250

DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Human), Biotinylated

4-PAJ282Hu01-Biotin
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with Biotin.

DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Mouse), Biotinylated

4-PAJ282Mu01-Biotin
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with Biotin.

Anti-8-hydroxyguanosine DNA/RNA Oxidative Damage Mouse Monoclonal Antibody

12501 100ug
EUR 380

Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Mouse), Biotinylated

4-PAA319Mu01-Biotin
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with Biotin.

Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Human, Mouse), Biotinylated

4-PAA319Hu01-Biotin
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with Biotin.

Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a) Polyclonal Antibody (Rat), Biotinylated

4-PAL534Ra01-Biotin
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a). This antibody is labeled with Biotin.
corbettresearch

Cell Cycle Checkpoints Cooperate to Suppress DNA– and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses

  • The DNA-dependent pattern recognition receptor, cGAS (cyclic GMP-AMP synthase), mediates communication between the DNA damage and the immune responses. Mitotic chromosome missegregation stimulates cGAS activity; however, it is unclear whether progression through mitosis is required for cancercell-intrinsic activation of anti-tumor immune responses.
  • Moreover, it is unknown whether cell cycle checkpoint disruption can restore responses in cancer cells that are recalcitrant to DNAdamage-induced inflammation. Here, we demonstrate that prolonged cell cycle arrest at the G2-mitosis boundary from either excessive DNA damage or CDK1 inhibition prevents inflammatory-stimulated gene expression and immune-mediated destruction of distal tumors. Remarkably, DNAdamage-induced inflammatory signaling is restored in a RIG-I-dependent manner upon concomitant disruption of p53 and the G2 checkpoint.
  • These findings link aberrant cell progression and p53 loss to an expanded spectrum of damage-associated molecular pattern recognition and have implications for the design of rational approaches to augment anti-tumor immune responses.
corbettresearch

corbettresearch

OxiSelect Oxidative RNA Damage ELISA Kit (8-OHG Quantitation), Trial Size

STA-325-T 32 assays
EUR 609.6
Description: Recently oxidative RNA damage has been described in conjunction with a wide variety of neurological diseases including Alzheimer?s disease, Parkinson?s disease, Dementia with Lewy Bodies, prion disease, and subacute sclerosing panencephalitis. We have developed an easy-to-use ELISA for the detection of the most common marker of RNA damage: 8-hydroxyguanosine (8-OHG).

OxiSelect™ Oxidative RNA Damage ELISA Kit (8-OHG Quantitation) (96 tests)

STA-325 96 assays
EUR 885

OxiSelect™ Oxidative RNA Damage ELISA Kit (8-OHG Quantitation) (5x96 tests)

STA-325-5 5 x 96 assays
EUR 3795

OxiSelect™ Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation) (1 plate)

STA-320 96 assays
EUR 885

OxiSelect™ Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation) (5 plates)

STA-320-5 5 x 96 assays
EUR 3795

OxiSelect™ Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation), Trial Size

STA-320-T 32 assays
EUR 440

DNA / RNA Damage Antibody

abx440040-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx440321-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx440602-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx440883-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx441164-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx441445-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx441726-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442007-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442288-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442569-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442850-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx443130-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx443410-100ug 100 ug
EUR 644.4

DNA / RNA Damage Antibody

abx443691-100ug 100 ug
EUR 678

DNA / RNA Damage Antibody

20-abx444884
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  • 100 ug
  • 25 ug

DNA / RNA Damage Antibody

abx443972-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx444253-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx444534-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx444884-100l 100 µl
EUR 337.5

DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody

abx148136-100ug 100 ug
EUR 526.8

DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody

20-abx005629
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  • 100 ul
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  • 20 ul
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DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody

20-abx321453
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  • 100 ul
  • 50 ul

DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody

20-abx320325
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  • 100 ul
  • 50 ul

DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody

abx005629-100l 100 µl
EUR 175

DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody

abx321453-100g 100 µg
EUR 350

DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody

abx321453-50g 50 µg
EUR 237.5

DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody

abx320325-100l 100 µl
EUR 350

DNA Oxidative Demethylase ALKBH2 (ALKBH2) Antibody

abx320325-50l 50 µl
EUR 237.5

DNA / RNA Damage Antibody (PE)

abx444253-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (APC)

abx442569-100l 100 µl
EUR 575

DNA / RNA Damage Antibody (HRP)

abx443410-100g 100 µg
EUR 562.5

DNA / RNA Damage Antibody (FITC)

abx443130-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (PerCP)

abx443972-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (Biotin)

abx442850-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (ATTO594)

abx440883-100g 100 µg
EUR 587.5

DNA / RNA Damage Antibody (ATTO390)

abx440040-200g 200 µg
EUR 587.5

DNA / RNA Damage Antibody (ATTO488)

abx440321-100g 100 µg
EUR 587.5

DNA/RNA Damage Antibody, Clone 15A3

SMC-155C 0.025mg
EUR 144
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

DNA/RNA Damage Antibody, Clone 15A3

SMC-155D 0.1mg
EUR 306
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

DNA/RNA Damage Antibody, Clone 15A3

SMC-155S 0.012mg
EUR 44
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

OASE00080-25UG - DNA/RNA Damage Antibody

OASE00080-25UG 25ug
EUR 199

OASE00081-100UG - DNA/RNA Damage Antibody

OASE00081-100UG 100ug
EUR 399

DNA/RNA Damage Antibody, Clone 15A3: APC

SMC-155D-APC 0.1mg
EUR 358
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC.

DNA/RNA Damage Antibody, Clone 15A3: HRP

SMC-155D-HRP 0.1mg
EUR 345
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with HRP.

DNA/RNA Damage Antibody, Clone 15A3: RPE

SMC-155D-RPE 0.1mg
EUR 355
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with RPE.

DNA/RNA Damage Antibody, Clone 15A3: FITC

SMC-155D-FITC 0.1mg
EUR 350
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with FITC.

DNA/RNA Damage Antibody, Clone 15A3: PerCP

SMC-155D-PCP 0.1mg
EUR 358
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PerCP.

DNA/RNA Damage Antibody, Clone 15A3: Biotin

SMC-155D-BI 0.1mg
EUR 354
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Biotin.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A565 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 565.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A633 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 633.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A655 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 655.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A680 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 680.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A700 0.1mg
EUR 453.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 700.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-APCCY7 0.1mg
EUR 540
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC/Cy7.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY350 0.1mg
EUR 471.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 350.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY405 0.1mg
EUR 457.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 405.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY488 0.1mg
EUR 445.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 488.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY594 0.1mg
EUR 447.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 594.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY633 0.1mg
EUR 441.6
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 633.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-P594 0.1mg
EUR 462
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PE/ATTO 594.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-STR 0.1mg
EUR 451.2
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Streptavidin.

DNA/RNA Damage Antibody, Clone 15A3: ATTO 390

SMC-155D-A390 0.1mg
EUR 360
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 390.

DNA/RNA Damage Antibody, Clone 15A3: ATTO 488

SMC-155D-A488 0.1mg
EUR 359
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 488.

DNA/RNA Damage Antibody, Clone 15A3: ATTO 594

SMC-155D-A594 0.1mg
EUR 359
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 594.

DNA/RNA Damage Antibody, Clone 15A3: Alkaline Phosphatase

SMC-155D-ALP 0.1mg
EUR 352
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Alkaline Phosphatase.

Human DNA Oxidative Demethylase ALKBH2 (ALKBH2) Protein

abx073206-20kDa1g 20 kDa; 1 g
EUR 225

Human DNA Oxidative Demethylase ALKBH2 (ALKBH2) Protein

abx073206-20kDa5g 20 kDa; 5 g
EUR 3550

Human DNA Oxidative Demethylase ALKBH2 (ALKBH2) Protein

abx073206-40kDa1g 40 kDa; 1 g
EUR 325

Recombinant Human DNA oxidative demethylase ALKBH2 (ALKBH2)

CSB-EP761219HU 4107 mg Ask for price

Oxidative Stress Responsive 1 (OXSR1) Antibody

abx114290-100l 100 µl
EUR 612.5

Oxidative Stress Responsive 1 (OXSR1) Antibody

abx212012-100l 100 µl
EUR 350

Oxidative Stress Responsive 1 (OXSR1) Antibody

abx212012-50l 50 µl
EUR 250

Oxidative Stress Responsive 1 (OXSR1) Antibody

abx213481-10l 10 µl
EUR 250

Oxidative Stress Responsive 1 (OXSR1) Antibody

abx236055-100g 100 µg
EUR 350

Oxidative Stress Responsive 1 (OXSR1) Antibody

abx146245-1096tests 10 × 96 tests Ask for price

Oxidative Stress Responsive 1 (OXSR1) Antibody

abx146245-596tests 5 × 96 tests Ask for price

Oxidative Stress Responsive 1 (OXSR1) Antibody

abx146245-96tests 96 tests
EUR 337.5

Oxidative Stress Responsive 1 (OXSR1) Antibody

abx325277-100g 100 µg
EUR 250

Oxidative Stress Responsive 1 (OXSR1) Antibody

abx325277-50g 50 µg
EUR 187.5

Oxidative Stress Responsive 1 (OXSR1) Antibody

abx325602-100g 100 µg
EUR 250

Oxidative Stress Responsive 1 (OXSR1) Antibody

abx325602-50g 50 µg
EUR 187.5

Oxidative-Stress Responsive 1 (OXSR1) Antibody

20-abx114290
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  • Ask for price
  • 150 ul
  • 50 ul

Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody

12503 100ug
EUR 230

Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody

12503-100 100ug
EUR 230

Anti-8-Oxo-A DNA/RNA Damage Mouse Monoclonal Antibody

12503-500 500ug
EUR 460

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

20-abx128290
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  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx146030-100ug 100 ug
EUR 469.2

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

20-abx114289
  • Ask for price
  • Ask for price
  • 150 ul
  • 50 ul

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx029975-400ul 400 ul
EUR 627.6

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx029975-80l 80 µl
EUR 343.2

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx236027-100ug 100 ug
EUR 610.8

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

20-abx173928
  • Ask for price
  • Ask for price
  • 1 mg
  • 200 ug

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx114289-100l 100 µl
EUR 612.5

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx128290-100l 100 µl
EUR 275

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx128290-1ml 1 ml
EUR 750

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx128290-200l 200 µl
EUR 337.5

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx173928-100l 100 µl
EUR 787.5

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx173928-1ml 1 ml Ask for price

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx173928-200l 200 µl Ask for price

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx029975-400l 400 µl
EUR 518.75

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx236027-100g 100 µg
EUR 350

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx146030-1096tests 10 × 96 tests Ask for price

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx146030-596tests 5 × 96 tests Ask for price

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Antibody

abx146030-96tests 96 tests
EUR 337.5

Human Oxidative Stress-Responsive 1 Protein (OXSR1) Antibody

33219-05111 150 ug
EUR 215

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody

abx122927-100ug 100 ug
EUR 469.2

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody

20-abx302885
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody

abx122927-100l 100 µl Ask for price

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody

abx122927-20l 20 µl
EUR 337.5

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody

abx122927-50l 50 µl Ask for price

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody

abx302885-100g 100 µg
EUR 362.5

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody

abx302885-20g 20 µg
EUR 162.5

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody

abx302885-50g 50 µg
EUR 250

Thiol Oxidative Stress Assay

1021 1 kit
EUR 460.8

Recombinant Human DNA oxidative demethylase ALKBH2 Protein, GST, E.coli-10ug

QP7771-ec-10ug 10ug
EUR 240

Recombinant Human DNA oxidative demethylase ALKBH2 Protein, GST, E.coli-1mg

QP7771-ec-1mg 1mg
EUR 1958.4

Recombinant Human DNA oxidative demethylase ALKBH2 Protein, GST, E.coli-50ug

QP7771-ec-50ug 50ug
EUR 315.6

Recombinant Human DNA oxidative demethylase ALKBH2 Protein, GST, E.coli-100ug

QP7771-ec-100ug 100ug
EUR 489.6

Recombinant Human DNA oxidative demethylase ALKBH2 Protein, GST, E.coli-200ug

QP7771-ec-200ug 200ug
EUR 760.8

Recombinant Human DNA oxidative demethylase ALKBH2 Protein, GST, E.coli-500ug

QP7771-ec-500ug 500ug
EUR 1272

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (HRP)

20-abx312498
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  • Ask for price
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  • Ask for price
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (FITC)

20-abx312499
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  • Ask for price
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (HRP)

abx312498-100g 100 µg
EUR 362.5

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (HRP)

abx312498-20g 20 µg
EUR 162.5

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (HRP)

abx312498-50g 50 µg
EUR 250

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (FITC)

abx312499-100g 100 µg
EUR 362.5

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (FITC)

abx312499-20g 20 µg
EUR 162.5

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (FITC)

abx312499-50g 50 µg
EUR 250

Oxidative Stress-Responsive Serine-Rich Protein 1 (OSER1) Antibody

20-abx318659
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (Biotin)

20-abx312500
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Rabbit polyclonal antibody to OXSR1 (oxidative-stress responsive 1)

TA308621 100 µl Ask for price

Oxidative Stress Responsive 1 Phospho-Thr185 (OXSR1 pT185) Antibody

abx325747-100g 100 µg
EUR 250

Oxidative Stress Responsive 1 Phospho-Thr185 (OXSR1 pT185) Antibody

abx325747-50g 50 µg
EUR 187.5

Oxidative Stress-Responsive Serine-Rich Protein 1 (OSER1) Antibody

abx318659-100l 100 µl
EUR 250

Oxidative Stress-Responsive Serine-Rich Protein 1 (OSER1) Antibody

abx318659-50l 50 µl
EUR 162.5

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (Biotin)

abx312500-100g 100 µg
EUR 362.5

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (Biotin)

abx312500-20g 20 µg
EUR 162.5

Oxidative Stress-Induced Growth Inhibitor 2 (OSGIN2) Antibody (Biotin)

abx312500-50g 50 µg
EUR 250

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Polyclonal Antibody

CAU22323-100ul 100ul
EUR 235.2

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Polyclonal Antibody

CAU22323-200ul 200ul
EUR 294

Rat Oxidative Stress Primer Library

ROSL-I 1 set
EUR 657.6

Polyclonal Antibody to Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1)

PAG202Hu01 100ul
EUR 245

Human Oxidative Stress Primer Library

HOSL-I 1 set
EUR 540

Mouse Oxidative Stress Primer Library

MOSL-I 1 set
EUR 657.6

Human Oxidative Stress-Responsive 1 Protein (OXSR1) Antibody (Biotin Conjugate)

33219-05121 150 ug
EUR 315

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Polyclonal Antibody (Human)

4-PAG202Hu01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1)

TBARS/Malondialdehyde Oxidative Stress Assay

1020 1 kit
EUR 373.2

Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1) Polyclonal Antibody (Human), APC

4-PAG202Hu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1). This antibody is labeled with APC.

A G-quadruplex-forming RNA aptamer binds to the MTG8 TAFH domain and dissociates the leukemic AML1-MTG8 fusion protein from DNA

MTG8 (RUNX1T1) is a fusion partner of AML1 (RUNX1) in the leukemic chromosome translocation t(8;21). The AML1-MTG8 fusion gene encodes a chimeric transcription factor. One of the highly conserved domains of MTG8 is TAFH which possesses homology with human TAF4 [TATA-box binding protein (TBP)-associated factor].
To obtain specific inhibitors of the AML1-MTG8 fusion protein, we isolated RNA aptamers against the MTG8 TAFH domain using Systematic Evolution of Ligands by EXponential enrichment (SELEX). All TAF aptamers contained guanine-rich sequences. Analyses of a TAF aptamer by NMR, CD and mutagenesis revealed that it forms a parallel G-quadruplex structure in the presence of K+ .
Furthermore, the aptamer could bind to the AML1-MTG8 fusion protein and dissociate the AML1-MTG8/DNA complex, suggesting that it can inhibit the dominant negative effects of AML1-MTG8 against normal AML1 function and serve as a potential therapeutic agent for leukemia.

DNARNA Heteroduplex Oligonucleotide for Highly Efficient Gene Silencing

Heteroduplex oligonucleotides (HDOs) were a novel type of nucleic acid drugs based on an antisense oligonucleotide (ASO) strand and its complementary RNA (cRNA ) strand.
HDOs were originally designed to improve the properties of RNase H-dependent ASOs and we reported in our first paper that HDOs conjugated with an α-tocopherol ligand (Toc-HDO ) based on a gapmer ASO showed 20 times higher silencing effect to liver apolipoprotein B (apoB) mRNA in vivo than the parent ASO.
Thereafter the HDO strategy was found to be also effective for improving the properties of ASOs modulating blood-brain barrier function and ASO antimiRs which are RNase H-independent ASOs. Therefore, the HDO strategy has been shown to be versatile technology platform to develop effective nucleic acid drugs.

Site-selective RNA Functionalization via DNA-induced Structure

Methods for RNA functionalization at specific sites are in high demand, but remain a challenge, particularly for RNAs produced by transcription rather than by total synthesis. Recent studies have described acylimidazole reagents that react in high yields at 2′-OH groups stochastically at non-base-paired regions, covering much of the RNA in scattered acyl esters.
Localized reactions, if possible, could prove useful in many applications, providing functional handles at specific sites and sequences of the biopolymer. Here we describe a DNA-directed strategy for in vitro functionalization of RNA at site-localized 2′-OH groups. The method, RNA Acylation at Induced Loops (RAIL), utilizes complementary helper DNA oligonucleotides that expose gaps or loops at selected positions while protecting the remainder in DNA-RNA duplexes.
Reaction with an acylimidazole reagent is then carried out, providing high yields of 2′-OH conjugation at predetermined sites. Experiments reveal optimal helper oligodeoxynucleotide designs and conditions for the reaction, and tests of the approach are carried out to control localized ribozyme activities and to label RNAs with dual-color fluorescent dyes. The RAIL approach offers a simple and novel strategy for site-specific labeling and control of RNAs, potentially of any length and origin.

Optimization of a Method for the Simultaneous Extraction of Polar and Non-Polar Oxylipin Metabolites, DNARNA, Small RNA, and Protein from a Single Small Tissue Sample

A more comprehensive picture of tissue biology can be obtained through the application and integration of multiple omic technologies. However, the common challenge in working with a precious sample is having a sample too small to separately extract analytes of interest for each experiment. Considering the high heterogeneity that can be present in a single tissue sample, extracting all biomolecules from a single and undivided tissue is preferable because it allows direct comparison of results.
Here, we combined a modified Folch extraction method with DNA, RNA, small RNA, and protein extraction using two commercial kits, which allowed us to extract polar metabolites and non-polar oxylipin metabolites, DNA, RNA, small RNA, and protein simultaneously from a small tissue sample. The method was validated in terms of quantity and quality of analytes for downstream analyses.

DNA / RNA Damage Antibody

abx441726-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442007-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442288-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442569-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx442850-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx443130-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx443410-100ug 100 ug
EUR 644.4

DNA / RNA Damage Antibody

abx443691-100ug 100 ug
EUR 678

DNA / RNA Damage Antibody

20-abx444884
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  • 100 ug
  • 25 ug

DNA / RNA Damage Antibody

abx443972-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx444253-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx444534-100ug 100 ug
EUR 661.2

DNA / RNA Damage Antibody

abx444884-100l 100 µl
EUR 337.5

DNA / RNA Damage Antibody (PE)

abx444253-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (APC)

abx442569-100l 100 µl
EUR 575

DNA / RNA Damage Antibody (HRP)

abx443410-100g 100 µg
EUR 562.5

DNA / RNA Damage Antibody (FITC)

abx443130-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (PerCP)

abx443972-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (Biotin)

abx442850-100g 100 µg
EUR 575

DNA / RNA Damage Antibody (ATTO594)

abx440883-100g 100 µg