
10
Sep
G-quadruplex DNA and RNA: Their roles in regulation of DNA replication and other biological functions
- G-quadruplex is one of the best-studied non-B type DNA that is now known to be prevalently present in the genomes of almost all the biological species. Recent studies reveal roles of G-quadruplex (G4) structures in various nucleic acids and chromosome transactions.
- In this short article, we will first describe recent findings on the roles of G4 in regulation of DNA replication. G4 is involved in regulation of spatio-temporal regulation of DNA replication through interaction with a specific binding protein, Rif1. This regulation is at least partially mediated by generation of specific chromatin architecture through Rif1-G4 interactions.
- We will also describe recent studies showing the potential roles of G4 in initiation of DNA replication. Next, we will present showcases of highly diversified roles of DNA G4 and RNA G4 in regulation of nucleic acid and chromosome functions. Finally, we will discuss how the formation of cellular G4 could be regulated.

corbettresearch
DNA / RNA Damage Antibody |
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abx440321-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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abx440602-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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abx440883-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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abx441164-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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abx441445-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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abx441726-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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abx442007-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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abx442850-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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abx443130-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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abx443410-100ug | Abbexa | 100 ug | EUR 644.4 |
DNA / RNA Damage Antibody |
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abx443691-100ug | Abbexa | 100 ug | EUR 678 |
DNA / RNA Damage Antibody |
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abx443972-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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abx442288-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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abx442569-100ug | Abbexa | 100 ug | EUR 661.2 |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155C | Stressmarq | 0.025mg | EUR 228 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D | Stressmarq | 0.1mg | EUR 398.4 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-A390 | Stressmarq | 0.1mg | EUR 454.8 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 390. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-A488 | Stressmarq | 0.1mg | EUR 453.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 488. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-A565 | Stressmarq | 0.1mg | EUR 453.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 565. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-A594 | Stressmarq | 0.1mg | EUR 453.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 594. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-A633 | Stressmarq | 0.1mg | EUR 453.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 633. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-A655 | Stressmarq | 0.1mg | EUR 453.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 655. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-A680 | Stressmarq | 0.1mg | EUR 453.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 680. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-A700 | Stressmarq | 0.1mg | EUR 453.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 700. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-ALP | Stressmarq | 0.1mg | EUR 446.4 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Alkaline Phosphatase. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-APC | Stressmarq | 0.1mg | EUR 452.4 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-APCCY7 | Stressmarq | 0.1mg | EUR 540 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC/Cy7. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-BI | Stressmarq | 0.1mg | EUR 448.8 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Biotin. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-DY350 | Stressmarq | 0.1mg | EUR 471.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 350. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-DY405 | Stressmarq | 0.1mg | EUR 457.2 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 405. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-DY488 | Stressmarq | 0.1mg | EUR 445.2 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 488. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-DY594 | Stressmarq | 0.1mg | EUR 447.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 594. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-DY633 | Stressmarq | 0.1mg | EUR 441.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 633. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-FITC | Stressmarq | 0.1mg | EUR 444 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with FITC. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-HRP | Stressmarq | 0.1mg | EUR 439.2 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with HRP. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-P594 | Stressmarq | 0.1mg | EUR 462 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PE/ATTO 594. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-PCP | Stressmarq | 0.1mg | EUR 452.4 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PerCP. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-RPE | Stressmarq | 0.1mg | EUR 450 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with RPE. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-STR | Stressmarq | 0.1mg | EUR 451.2 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Streptavidin. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155S | Stressmarq | 0.012mg | EUR 78 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated. |
Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (APC) |
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abx442602-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Human), APC |
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4-PAJ282Hu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with APC. |
DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Mouse), APC |
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4-PAJ282Mu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with APC. |
Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Mouse), APC |
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4-PAA319Mu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with APC. |
DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Human), APC-Cy7 |
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4-PAJ282Hu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with APC-Cy7. |
DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Mouse), APC-Cy7 |
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4-PAJ282Mu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with APC-Cy7. |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
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abx232284-100ug | Abbexa | 100 ug | EUR 577.2 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
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20-abx333999 | Abbexa |
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DNA Damage-Binding Protein 2 (DDB2) Antibody |
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20-abx338922 | Abbexa |
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Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Human, Mouse), APC |
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4-PAA319Hu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human, Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with APC. |
Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Mouse), APC-Cy7 |
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4-PAA319Mu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with APC-Cy7. |
DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
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20-abx241498 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx103576 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx176186 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx172142 | Abbexa |
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DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
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20-abx213754 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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abx332226-100ul | Abbexa | 100 ul | EUR 510 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx326210 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx112119 | Abbexa |
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DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
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20-abx112120 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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abx026524-400ul | Abbexa | 400 ul | EUR 627.6 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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abx026524-80l | Abbexa | 80 µl | EUR 343.2 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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abx027183-400ul | Abbexa | 400 ul | EUR 627.6 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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abx027183-80l | Abbexa | 80 µl | EUR 343.2 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx125748 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx125750 | Abbexa |
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DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
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20-abx123209 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx129884 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx329652 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx000607 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx004988 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx301173 | Abbexa |
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P53 And DNA Damage Regulated 1 (PDRG1) Antibody |
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abx236289-100ug | Abbexa | 100 ug | EUR 577.2 |
P53 And DNA Damage Regulated 1 (PDRG1) Antibody |
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abx148746-100ug | Abbexa | 100 ug | EUR 526.8 |
P53 And Dna Damage Regulated 1 (PDRG1) Antibody |
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20-abx114308 | Abbexa |
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P53 And DNA Damage Regulated 1 (PDRG1) Antibody |
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20-abx328877 | Abbexa |
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P53 And DNA Damage Regulated 1 (PDRG1) Antibody |
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abx340215-100ug | Abbexa | 100 ug | EUR 469.2 |
P53 And DNA Damage Regulated 1 (PDRG1) Antibody |
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20-abx008020 | Abbexa |
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P53 And DNA Damage Regulated 1 (PDRG1) Antibody |
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20-abx014692 | Abbexa |
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P53 And DNA Damage Regulated 1 (PDRG1) Antibody |
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20-abx301702 | Abbexa |
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DNA Damage-Binding Protein 1 (DDB1) Antibody (HRP) |
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20-abx335376 | Abbexa |
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DNA Damage-Binding Protein 2 (DDB2) Antibody (HRP) |
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20-abx335379 | Abbexa |
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OxiSelect Nitrosative DNA/RNA Damage ELISA Kit (8-Nitroguanine Quantitation) |
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STA-825 | Cell Biolabs | 96 assays | EUR 957.6 |
Description: The OxiSelect Nitrosative DNA/RNA Damage ELISA Kit is a competitive enzyme immunoassay developed for rapid detection and quantitation of 8-nitroguanine in urine, serum, or plasma samples. |
OxiSelect Nitrosative DNA/RNA Damage ELISA Kit (8-Nitroguanine Quantitation) |
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STA-825-5 | Cell Biolabs | 5 x 96 assays | EUR 3888 |
Description: The OxiSelect Nitrosative DNA/RNA Damage ELISA Kit is a competitive enzyme immunoassay developed for rapid detection and quantitation of 8-nitroguanine in urine, serum, or plasma samples. |
Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody |
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20-abx316281 | Abbexa |
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Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody |
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20-abx210264 | Abbexa |
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Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody |
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abx235072-100ug | Abbexa | 100 ug | EUR 661.2 |
Mediator of DNA Damage Checkpoint 1 (MDC1) Antibody |
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abx412564-01ml | Abbexa | 0.1 ml | EUR 844.8 |
Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody |
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abx444922-100ug | Abbexa | 100 ug | EUR 594 |
DNA Damage-Binding Protein 1 (DDB1) Antibody (FITC) |
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20-abx335377 | Abbexa |
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DNA Damage-Binding Protein 2 (DDB2) Antibody (FITC) |
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20-abx335380 | Abbexa |
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Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody |
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20-abx005807 | Abbexa |
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DNA Damage Induced Apoptosis Suppressor (DDIAS) Antibody |
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20-abx323435 | Abbexa |
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Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Human, Mouse), APC-Cy7 |
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4-PAA319Hu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human, Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with APC-Cy7. |
Damage Specific DNA Binding Protein 1 (DDB1) Antibody |
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abx232285-100ug | Abbexa | 100 ug | EUR 610.8 |
Damage Specific DNA Binding Protein 2 (DDB2) Antibody |
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abx232286-100ug | Abbexa | 100 ug | EUR 577.2 |
Damage Specific DNA Binding Protein 1 (DDB1) Antibody |
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20-abx242438 | Abbexa |
|
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Damage Specific DNA Binding Protein 1 (DDB1) Antibody |
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20-abx242444 | Abbexa |
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Damage Specific DNA Binding Protein 2 (DDB2) Antibody |
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20-abx225140 | Abbexa |
|
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Damage Specific DNA Binding Protein 1 (DDB1) Antibody |
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abx219380-100ug | Abbexa | 100 ug | EUR 526.8 |
Damage Specific DNA Binding Protein 1 (DDB1) Antibody |
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20-abx141699 | Abbexa |
|
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Damage Specific DNA Binding Protein 1 (DDB1) Antibody |
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abx412503-01mg | Abbexa | 0.1 mg | EUR 961.2 |
DNA Damage-Binding Protein 1 (DDB1) Antibody (Biotin) |
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20-abx335378 | Abbexa |
|
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DNA Damage-Binding Protein 2 (DDB2) Antibody (Biotin) |
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20-abx335381 | Abbexa |
|
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Damage Specific DNA Binding Protein 1 (DDB1) Antibody |
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20-abx111958 | Abbexa |
|
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Damage Specific DNA Binding Protein 2 (DDB2) Antibody |
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20-abx111959 | Abbexa |
|
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Damage Specific DNA Binding Protein 2 (DDB2) Antibody |
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20-abx128508 | Abbexa |
|
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Damage Specific DNA Binding Protein 2 (DDB2) Antibody |
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20-abx130944 | Abbexa |
|
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Damage Specific DNA Binding Protein 1 (DDB1) Antibody |
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abx432057-200ul | Abbexa | 200 ul | EUR 460.8 |
Damage Specific DNA Binding Protein 2 (DDB2) Antibody |
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20-abx001528 | Abbexa |
|
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Damage Specific DNA Binding Protein 1 (DDB1) Antibody |
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20-abx002127 | Abbexa |
|
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Damage Specific DNA Binding Protein 1 (DDB1) Antibody |
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abx159468-100ul | Abbexa | 100 ul | EUR 560.4 |
Damage Specific DNA Binding Protein 1 (DDB1) Antibody |
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abx159469-100ul | Abbexa | 100 ul | EUR 560.4 |
P53 And DNA Damage Regulated 1 (PDRG1) Antibody (HRP) |
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20-abx311435 | Abbexa |
|
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody (HRP) |
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20-abx303605 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody (FITC) |
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20-abx303606 | Abbexa |
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P53 And DNA Damage Regulated 1 (PDRG1) Antibody (FITC) |
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20-abx311436 | Abbexa |
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EpiQuik Nitrosative (8-Nitroguanine) DNA/RNA Damage Quantification Kit (Colorimetric) |
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P-6009 | EpiGentek |
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DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody |
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20-abx213755 | Abbexa |
|
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DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody |
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20-abx213756 | Abbexa |
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DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody |
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abx140150-01mg | Abbexa | 0.1 mg | EUR 510 |
DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody |
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20-abx112121 | Abbexa |
|
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DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody |
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20-abx302163 | Abbexa |
|
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Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a) Polyclonal Antibody (Rat), APC |
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4-PAL534Ra01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a). This antibody is labeled with APC. |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin) |
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20-abx272570 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin) |
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20-abx303607 | Abbexa |
|
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P53 And DNA Damage Regulated 1 (PDRG1) Antibody (Biotin) |
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20-abx311437 | Abbexa |
|
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Growth Arrest And DNA Damage Inducible Protein Gamma (GADD45g) Polyclonal Antibody (Mouse), APC |
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4-PAL536Mu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Growth Arrest And DNA Damage Inducible Protein Gamma (GADD45g). This antibody is labeled with APC. |
Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (HRP) |
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20-abx316282 | Abbexa |
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Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (RPE) |
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abx444286-100ug | Abbexa | 100 ug | EUR 661.2 |
Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (HRP) |
|||
abx443443-100ug | Abbexa | 100 ug | EUR 644.4 |
Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ALP) |
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abx442321-100ug | Abbexa | 100 ug | EUR 661.2 |
Vaccination with Messenger RNA: A Promising Alternative to DNA Vaccination
- The first proof-of-concept studies about the feasibility of genetic vaccines were published over three decades ago, opening the way for future development. The idea of nonviral antigen delivery had multiple advantages over the traditional live or inactivated pathogen-based vaccines, but a great deal of effort had to be invested to turn the idea of genetic vaccination into reality.
- Although early proof-of-concept studies were groundbreaking, they also showed that numerous aspects of genetic vaccines needed to be improved. Until the early 2000s, the vast majority of effort was invested into the development of DNA vaccines due to the potential issues of instability and low in vivo translatability of messenger RNA (mRNA).
- In recent years, numerous studies have demonstrated the outstanding abilities of mRNA to elicit potent immune responses against infectious pathogens and different types of cancer, making it a viable platform for vaccine development. Multiple mRNA vaccine platforms have been developed and evaluated in small and large animals and humans and the results seem to be promising. RNA-based vaccines have important advantages over other vaccine approaches including outstanding efficacy, safety, and the potential for rapid, inexpensive, and scalable production.
- There is a substantial investment by new mRNA companies into the development of mRNA therapeutics, particularly vaccines, increasing the number of basic and translational research publications and human clinical trials underway. This review gives a broad overview about genetic vaccines and mainly focuses on the past and present of mRNA vaccines along with the future directions to bring this potent vaccine platform closer to therapeutic use.
Atypical structures of GAA/TTC trinucleotide repeats underlying Friedreich’s ataxia: DNA triplexes and RNA/DNA hybrids
Expansion of the GAA/TTC repeats in the first intron of the FXN gene causes Friedreich’s ataxia. Non-canonical structures are linked to this expansion. DNA triplexes and R-loops are believed to arrest transcription, which results in frataxin deficiency and eventual neurodegeneration.
We present a systematic in silico characterization of the possible DNA triplexes that could be assembled with GAA and TTC strands; the two hybrid duplexes [r(GAA):d(TTC) and d(GAA):r(UUC)] in an R-loop; and three hybrid triplexes that could form during bidirectional transcription when the non-template DNA strand bonds with the hybrid duplex (collapsed R-loops, where the two DNA strands remain antiparallel).
For both Y·R:Y and R·R:Y DNA triplexes, the parallel third strand orientation is more stable; both parallel and antiparallel protonated d(GA+A)·d(GAA):d(TTC) triplexes are stable. Apparent contradictions in the literature about the R·R:Y triplex stability is probably due to lack of molecular resolution, since shifting the third strand by a single nucleotide alters the stability ranking.
In the collapsed R-loops, antiparallel d(TTC+)·d(GAA):r(UUC) is unstable, while parallel d(GAA)·r(GAA):d(TTC) and d(GA+A)·r(GAA):d(TTC) are stable. In addition to providing new structural perspectives for specific therapeutic aims, our results contribute to a systematic structural basis for the emerging field of quantitative R-loop biology.
DNA / RNA Damage Antibody |
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abx441445-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
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abx441726-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
|||
abx442007-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
|||
abx442850-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
|||
abx443130-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
|||
abx443410-100ug | Abbexa | 100 ug | EUR 644.4 |
DNA / RNA Damage Antibody |
|||
abx443691-100ug | Abbexa | 100 ug | EUR 678 |
DNA / RNA Damage Antibody |
|||
abx443972-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
|||
abx442288-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA / RNA Damage Antibody |
|||
abx442569-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA Damage-Binding Protein 1 (DDB1) Antibody (Biotin) |
|||
20-abx335378 | Abbexa |
|
|
DNA Damage-Binding Protein 2 (DDB2) Antibody (Biotin) |
|||
20-abx335381 | Abbexa |
|
|
Monoclonal antibody for DNA/RNA Damage |
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SMC-155C | Stressmarq | 0.025mg | EUR 228 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D | Stressmarq | 0.1mg | EUR 398.4 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-A390 | Stressmarq | 0.1mg | EUR 454.8 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 390. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-A488 | Stressmarq | 0.1mg | EUR 453.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 488. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-A565 | Stressmarq | 0.1mg | EUR 453.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 565. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-A594 | Stressmarq | 0.1mg | EUR 453.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 594. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-A633 | Stressmarq | 0.1mg | EUR 453.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 633. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-A655 | Stressmarq | 0.1mg | EUR 453.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 655. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-A680 | Stressmarq | 0.1mg | EUR 453.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 680. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-A700 | Stressmarq | 0.1mg | EUR 453.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 700. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-ALP | Stressmarq | 0.1mg | EUR 446.4 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Alkaline Phosphatase. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-APC | Stressmarq | 0.1mg | EUR 452.4 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-APCCY7 | Stressmarq | 0.1mg | EUR 540 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC/Cy7. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-BI | Stressmarq | 0.1mg | EUR 448.8 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Biotin. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-DY350 | Stressmarq | 0.1mg | EUR 471.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 350. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-DY405 | Stressmarq | 0.1mg | EUR 457.2 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 405. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-DY488 | Stressmarq | 0.1mg | EUR 445.2 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 488. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-DY594 | Stressmarq | 0.1mg | EUR 447.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 594. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-DY633 | Stressmarq | 0.1mg | EUR 441.6 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 633. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-FITC | Stressmarq | 0.1mg | EUR 444 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with FITC. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-HRP | Stressmarq | 0.1mg | EUR 439.2 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with HRP. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-P594 | Stressmarq | 0.1mg | EUR 462 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PE/ATTO 594. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-PCP | Stressmarq | 0.1mg | EUR 452.4 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PerCP. |
Monoclonal antibody for DNA/RNA Damage |
|||
SMC-155D-RPE | Stressmarq | 0.1mg | EUR 450 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with RPE. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155D-STR | Stressmarq | 0.1mg | EUR 451.2 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Streptavidin. |
Monoclonal antibody for DNA/RNA Damage |
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SMC-155S | Stressmarq | 0.012mg | EUR 78 |
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated. |
P53 And DNA Damage Regulated 1 (PDRG1) Antibody (Biotin) |
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20-abx311437 | Abbexa |
|
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin) |
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20-abx272570 | Abbexa |
|
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody (Biotin) |
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20-abx303607 | Abbexa |
|
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Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (Biotin) |
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20-abx316284 | Abbexa |
|
|
Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (Biotin) |
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abx442882-100ug | Abbexa | 100 ug | EUR 661.2 |
DNA Damage Inducible Transcript 4 Like (DDIT4L) Antibody (Biotin) |
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20-abx314619 | Abbexa |
|
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Growth Arrest And DNA Damage-Inducible, Alpha (GADD45A) Antibody (Biotin) |
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20-abx303924 | Abbexa |
|
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DNA Damage Regulated Autophagy Modulator Protein 1 (DRAM1) Antibody (Biotin) |
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20-abx316409 | Abbexa |
|
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Growth Arrest And DNA Damage Inducible Protein Beta (GADD45B) Antibody (Biotin) |
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20-abx303927 | Abbexa |
|
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Growth Arrest And DNA Damage-Inducible Protein GADD45 Gamma (GADD45G) Antibody (Biotin) |
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20-abx303930 | Abbexa |
|
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DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Human), Biotinylated |
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4-PAJ282Hu01-Biotin | Cloud-Clone |
|
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Description: A Rabbit polyclonal antibody against Human DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with Biotin. |
DNA Damage Inducible Transcript 3 (DDIT3) Polyclonal Antibody (Mouse), Biotinylated |
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4-PAJ282Mu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse DNA Damage Inducible Transcript 3 (DDIT3). This antibody is labeled with Biotin. |
Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Mouse), Biotinylated |
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4-PAA319Mu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with Biotin. |
Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody (Human, Mouse), Biotinylated |
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4-PAA319Hu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human, Mouse Damage Specific DNA Binding Protein 2 (DDB2). This antibody is labeled with Biotin. |
Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a) Polyclonal Antibody (Rat), Biotinylated |
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4-PAL534Ra01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a). This antibody is labeled with Biotin. |
Growth Arrest And DNA Damage Inducible Protein Gamma (GADD45g) Polyclonal Antibody (Mouse), Biotinylated |
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4-PAL536Mu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Growth Arrest And DNA Damage Inducible Protein Gamma (GADD45g). This antibody is labeled with Biotin. |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
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abx232284-100ug | Abbexa | 100 ug | EUR 577.2 |
DNA Damage-Binding Protein 1 (DDB1) Antibody |
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20-abx333999 | Abbexa |
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DNA Damage-Binding Protein 2 (DDB2) Antibody |
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20-abx338922 | Abbexa |
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Growth Arrest And DNA Damage Inducible Protein Beta (GADD45b) Polyclonal Antibody (Human, Mouse), Biotinylated |
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4-PAL535Hu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human, Mouse Growth Arrest And DNA Damage Inducible Protein Beta (GADD45b). This antibody is labeled with Biotin. |
DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
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20-abx241498 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx103576 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx176186 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx172142 | Abbexa |
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DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
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20-abx213754 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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abx332226-100ul | Abbexa | 100 ul | EUR 510 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx326210 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx112119 | Abbexa |
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DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
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20-abx112120 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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abx026524-400ul | Abbexa | 400 ul | EUR 627.6 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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abx026524-80l | Abbexa | 80 µl | EUR 343.2 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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abx027183-400ul | Abbexa | 400 ul | EUR 627.6 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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abx027183-80l | Abbexa | 80 µl | EUR 343.2 |
DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx125748 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx125750 | Abbexa |
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DNA Damage Inducible Transcript 4 (DDIT4) Antibody |
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20-abx123209 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx129884 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx329652 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx000607 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx004988 | Abbexa |
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DNA Damage Inducible Transcript 3 (DDIT3) Antibody |
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20-abx301173 | Abbexa |
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P53 And DNA Damage Regulated 1 (PDRG1) Antibody |
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abx236289-100ug | Abbexa | 100 ug | EUR 577.2 |
P53 And DNA Damage Regulated 1 (PDRG1) Antibody |
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abx148746-100ug | Abbexa | 100 ug | EUR 526.8 |
P53 And Dna Damage Regulated 1 (PDRG1) Antibody |
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20-abx114308 | Abbexa |
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P53 And DNA Damage Regulated 1 (PDRG1) Antibody |
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20-abx328877 | Abbexa |
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P53 And DNA Damage Regulated 1 (PDRG1) Antibody |
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abx340215-100ug | Abbexa | 100 ug | EUR 469.2 |
P53 And DNA Damage Regulated 1 (PDRG1) Antibody |
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20-abx008020 | Abbexa |
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P53 And DNA Damage Regulated 1 (PDRG1) Antibody |
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20-abx014692 | Abbexa |
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P53 And DNA Damage Regulated 1 (PDRG1) Antibody |
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20-abx301702 | Abbexa |
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Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a) Polyclonal Antibody (Human, Mouse), Biotinylated |
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4-PAL534Hu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human, Mouse Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a). This antibody is labeled with Biotin. |
DNA Damage-Binding Protein 1 (DDB1) Antibody (HRP) |
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20-abx335376 | Abbexa |
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DNA Damage-Binding Protein 2 (DDB2) Antibody (HRP) |
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20-abx335379 | Abbexa |
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OxiSelect Nitrosative DNA/RNA Damage ELISA Kit (8-Nitroguanine Quantitation) |
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STA-825 | Cell Biolabs | 96 assays | EUR 957.6 |
Description: The OxiSelect Nitrosative DNA/RNA Damage ELISA Kit is a competitive enzyme immunoassay developed for rapid detection and quantitation of 8-nitroguanine in urine, serum, or plasma samples. |
OxiSelect Nitrosative DNA/RNA Damage ELISA Kit (8-Nitroguanine Quantitation) |
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STA-825-5 | Cell Biolabs | 5 x 96 assays | EUR 3888 |
Description: The OxiSelect Nitrosative DNA/RNA Damage ELISA Kit is a competitive enzyme immunoassay developed for rapid detection and quantitation of 8-nitroguanine in urine, serum, or plasma samples. |
Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody |
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20-abx316281 | Abbexa |
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Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody |
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20-abx210264 | Abbexa |
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Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody |
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abx235072-100ug | Abbexa | 100 ug | EUR 661.2 |
Mediator of DNA Damage Checkpoint 1 (MDC1) Antibody |
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abx412564-01ml | Abbexa | 0.1 ml | EUR 844.8 |
Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody |
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abx444922-100ug | Abbexa | 100 ug | EUR 594 |
DNA Damage-Binding Protein 1 (DDB1) Antibody (FITC) |
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20-abx335377 | Abbexa |
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DNA Damage-Binding Protein 2 (DDB2) Antibody (FITC) |
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20-abx335380 | Abbexa |
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Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody |
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20-abx005807 | Abbexa |
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DNA Damage Induced Apoptosis Suppressor (DDIAS) Antibody |
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20-abx323435 | Abbexa |
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Damage Specific DNA Binding Protein 1 (DDB1) Antibody |
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abx232285-100ug | Abbexa | 100 ug | EUR 610.8 |